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Heat-induced denaturation and aggregation of protein in quinoa (Chenopodium quinoa Willd.) seeds and whole meal KU Leuven

Julie Van de Vondel, Marlies Lambrecht, Jan Delcour
Physical barriers hinder about 20-25% of the protein from being extracted from whole meal. Heat-induced denaturation and aggregation of protein in quinoa seeds and in whole meal was investigated. Maximally 37% of the protein in seeds covalently aggregate when boiling for 15 min. Although embryonic cell walls surrounding protein bodies remain intact during boiling of seeds, protein aggregation is not hindered. 11S Globulin monomers first ...

Stable prevalence of triazole-resistance in Aspergillus fumigatus complex clinical isolates in a Belgian tertiary care center from 2016 to 2020. KU Leuven

Agustìn Reséndiz Sharpe, Rita Merckx, Paul E Verweij, Johan Maertens, Katrien Lagrou
BACKGROUND: Prevalence reports of triazole-resistance in Aspergillus fumigatus differ between countries and centers and may likewise vary over time. Continuous local surveillance programs to establish the evolving epidemiology of triazole-resistance in A. fumigatus are crucial to guide therapeutic recommendations. Here, we determined the prevalence of triazole-resistance in A. fumigatus complex culture-positive patients at the tertiary care ...

Thoracic Anesthesia during the COVID-19 Pandemic: 2021 Updated Recommendations by the European Association of Cardiothoracic Anaesthesiology and Intensive Care (EACTAIC) Thoracic Subspecialty Committee. KU Leuven

Mert Şentürk, Mohamed R El Tahan, Ben Shelley, Laszlo L Szegedi, Federico Piccioni, Marc-Joseph Licker, Waheedullah Karzai, Manuel Granell Gil, Vojislava Neskovic, Caroline Vanpeteghem, et al.
The novel coronavirus pandemic has radically changed the landscape of normal surgical practice. Lifesaving cancer surgery, however, remains a clinical priority, and there is an increasing need to fully define the optimal oncologic management of patients with varying stages of lung cancer, allowing prioritization of which thoracic procedures should be performed in the current era. Healthcare providers and managers should not ignore the risk of a ...

Mixed method evaluation of the CEBHA+ integrated knowledge translation approach Vrije Universiteit Brussel

Lisa M Pfadenhauer, Tanja Grath, Peter Delobelle, Nasreen Jessani, Joerg J Meerpohl, Anke Rohwer, Bey-Marrié Schmidt, Ingrid Toews, Ann R Akiteng, Gertrude Chapotera, et al.

BACKGROUND: The Collaboration for Evidence-based Healthcare and Public Health in Africa (CEBHA+) is a research consortium concerned with the prevention, diagnosis and treatment of non-communicable diseases. CEBHA+ seeks to engage policymakers and practitioners throughout the research process in order to build lasting relationships, enhance evidence uptake, and create long-term capacity among partner institutions in Ethiopia, Malawi, Rwanda, ...

Individualized mechanical ventilation in a shared ventilator setting: limits, safety and technical details. Vrije Universiteit Brussel

Michiel Stiers, M Mergeay, Hannah Pinson, Luc Janssen, Evy Voets, Harald De Cauwer, Tom Schepens

The COVID-19 pandemic has resulted in an increased need for ventilators. The potential to ventilate more than one patient with a single ventilator, a so-called split ventilator setup, provides an emergency solution. Our hypothesis is that ventilation can be individualized by adding a flow restrictor to limit tidal volumes, add PEEP, titrate FiO2 and monitor ventilation. This way we could enhance optimization of patient safety and clinical ...

Identity Leadership, Employee Burnout and the Mediating Role of Team Identification: Evidence from the Global Identity Leadership Development Project KU Leuven

Rolf van Dick, Berrit L Cordes, Jérémy E Lemoine, Niklas K Steffens, S Alexander Haslam, Serap Akfırat, Christine Joy A Ballada, Tahir Bazarov, John Jamir Benzon R Aruta, Lorenzo Avanzi, et al.
Do leaders who build a sense of shared social identity in their teams thereby protect them from the adverse effects of workplace stress? This is a question that the present paper explores by testing the hypothesis that identity leadership contributes to stronger team identification among employees and, through this, is associated with reduced burnout. We tested this model with unique datasets from the Global Identity Leadership Development ...

Investigation of starch functionality and digestibility in white wheat bread produced from a recipe containing added maltogenic amylase or amylomaltase KU Leuven

Konstantinos Korompokis, Lomme Deleu, Niels De Brier, Jan Delcour
In the crumb of fresh white wheat bread, starch is fully gelatinized. Its molecular and three-dimensional structure are major factors limiting the rate of its digestion. The aim of this study was to in situ modify starch during bread making with starch-modifying enzymes (maltogenic amylase and amylomaltase) and to investigate the impact thereof on bread characteristics, starch retrogradation and digestibility. Maltogenic amylase treatment ...

Population pharmacokinetics of cefazolin in maternal and umbilical cord plasma, and simulated exposure in term neonates. KU Leuven

Omar Elkayal, Karel Allegaert, Isabel Spriet, Anne Smits, Marie-Christine Seghaye, Corinne Charlier, Erwin Dreesen
BACKGROUND: Intra-partum cefazolin is used to prevent group B Streptococcus (GBS) vertical transmission in mothers allergic to penicillin without a history of anaphylaxis. OBJECTIVES: To investigate the maternal cefazolin dose-exposure relationship and subsequent maternal and neonatal target attainment at delivery. METHODS: Data were obtained from 24 healthy, GBS-colonized pregnant women (20-41 years), undergoing vaginal delivery (gestational ...