Projects
Understanding functioning and evolution of bird middle ear mechanics through high-realism finite element modelling and system identification. University of Antwerp
Comprehending the biomechanics of the eardrum through advanced finite element modeling and newly developed stroboscopic digital holography. University of Antwerp
Cognitive robotic control guided by intra-operative medical imagin. KU Leuven
Electrical interaction with the abnormal brain cavity wall to reduce cavity-related symptoms: proof-of-concept study in the rat KU Leuven
On each neurosurgery and neuroanatomy ward around the world lie patients with an abnormal brain cavity (aBC). Such an aBC develops because neurons are lost as a result of brain damage due to e.g. a stroke or traumatic brain injury. Symptoms associated with an aBC range from motor impairment such as paresis to psychiatric symptoms such as depression. Despite a wide range of available therapies, these symptoms often remain, even years ...
A multilevel, integrative approach for the study of cellmatrix mechanics and mechanotransduction during cell adhesion. KU Leuven
Structural and mechanical characterization of the superior sagittal sinus - bridging vein complex. KU Leuven
Structural and mechanical characterization of thet superior sagittal sinus - bridging vein complex. KU Leuven
Acute subdural hematoma (ASDH) is one of the most frequent lesions inside the head observed in victims of bicycle related accidents. In nearly one third of the ASDH cases, the etiopathology directly relates to the rupture of a bridging vein (BV) which drains blood from the cerebral cortex into the superior sagittal sinus (SSS). To study the biomechanics of ASDH and other traumatic brain injuries and to assess the efficacy and improve the ...
Evaluation of galectin-1 targeting drugs in combination with chemo-immunotherapy in the treatment of high-grade glioma. KU Leuven
Glioblastoma multiforme (GBM) is until today, one of the most aggressive and lethal tumors. Recent advances in surgery, chemo-and radiotherapy were not able to induce a significant shift in prognosis for these patients, and therefore this clearly presents an unmet medical need. Galectin-1 (Gal-1) is a naturally occurring galactose-binding lectin, which is overexpressed in glioblastoma multiforme (GBM). Gal-1 is associated with tumor ...