Do Advanced Glycation End products (AGEs) play a role in heart failure? Hasselt University
Heart failure (HF) results from a series of complex processes that are still incompletely understood. Treatments of HF patients tend to relieve symptomatic disorders, improve outcome but fail to completely reverse the adverse phenotype. Several clinical and experimental studies support the view that Advanced Glycation End products (AGEs) have a significant role in cardiac dysfunction. AGEs are a heterogeneous family of compounds, composed of ...