Projects
Point-of-care testing for free bilirubin diagnosis (FREEBDX). University of Antwerp
Quantitative model-based tomography. University of Antwerp
Investigation on a critical time window for gait training in stroke rehabilitation. University of Antwerp
Understanding 3D nuclear DNA architecture and gene expression in single cells: a comprehensive survey in the first days of life. KU Leuven
Our understanding of the organisation of DNA present in a cell’s nucleus into higher order structures is rudimentary, but crucial to comprehend varying gene expression and phenotypes of cells in normal and diseased conditions. In particular in the first cell cycles of human and animal life following fertilisation drastic changes occur in the DNA architecture of nuclei as well as in gene expression, whereby cells become committed and ...
Single-cell omics in high throughput and at spatial resolution KU Leuven
A human body comprises 10 to 100 billion cells (= 10 to 100 x 1000.000.000.000 cells). As most of our organ functions are executed by the concerted action of those individual cells in a spatially organised context, it is paramount to research individual cells in their native spatial context. This is not only important to understand normal organ development and function, but also to investigate how (subpopulations of) cells are perturbed in ...