Projects
Dose Verification of basic and advanced radiotherapy techniques in Belgium Hasselt University
Design, synthesis and evaluation of new potent radioligands for PDE7 imaging in the brain. University of Antwerp
Development of Temporal Separation Methods for Simultaneous Dual Tracer PET Imaging with in vivo Validation for Applications in Oncology and Neurology. University of Antwerp
Activity-based probes for PET imaging of protease activity. University of Antwerp
Molecular imaging for early response assessment of drugs targeting the PI3K/mTOR pathway in an HER-2 amplified breast cancer model. University of Antwerp
Rigid Motion Correction for Positron Emission Tomography Brain Imaging KU Leuven
During a positron emission tomography (PET) scan the subject is required to be completely stationary for the duration of the scan. Any motion of the subject will translate into motion blur in the final reconstructed image and may reduce the diagnostic value of the image. Motion during a PET scan can be classified into two main categories: non-rigid and rigid motion. Non-rigid motion deforms the subject and is primarily caused by motion in the ...
Synthesis and biological evaluation of carbon-11 and fluorine-18 labelled P2X7-receptor ligands for diagnosis of neurological diseases using positron emission tomography KU Leuven
Neurodegenerative brain diseases such as Alzheimer’s disease, Parkinson’s disease, multiple sclerosis and amyotrophic lateral sclerosis are associated with progressive neuronal cell loss and neuroinflammation. Neuroinflammatory processes can be described as a release of neurotoxic substances which accelerate disease progression. As the incidence of neurodegenerative disorders increases and treatment is in most cases only effective in the ...