Improving frontline treatment for malignant pleural mesothelioma with concomitant platinum/pemetrexed-based chemotherapy and Wilms' tumor protein 1 (WT1)-targeted dendritic cell immunotherapy. University of Antwerp
Laboratory for Experimental Hematology (LEH), Vaccine & Infectious Disease Institute (VAXINFECTIO)
The prognosis of patients diagnosed with malignant pleural mesothelioma (MPM) remains dismal with a median overall survival from diagnosis of only 12 months. The steadily increasing incidence of MPM along with the limited efficacy of the currently available treatment options for MPM prompts a search for new, more effective therapeutic modalities and strategies. Dendritic cells · (DCs), the immune system’s quinte-ssential antigen-presenting ...