Projects
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On 14/06/2018 the Research Council has approved the short stay of dr. Lucélia Borgo (University of São Paulo, Brazilië) at UHasselt, chargeable to the BOF-program 'Short Stays'. During this stay, dr. Lucélia Borgo will perform research in collaboration with prof. Jaco Vangronsveld (research group CMKMB). The stay will take place in 2018-2019.
Investigation of hybrid phase change materials by dielectric and impedance spectroscopy KU Leuven
Investigation of hybrid phase change materials by dielectric and impedance spectroscopy
The future of TRACE: a Belgian PDX platform boosting cutting edge cancer research KU Leuven
In the near future, TRACE had the ambition to reinforce its position as the leading Belgian platform for preclinical research by expanding the collection models and engineer them to better mimic human cancers.
Understanding intra-tumor heterogeneity in glioblastoma in space and in time. KU Leuven
Intra-tumor heterogeneity is the main obstacle to effective cancer treatment and personalized medicine. The mechanistic underpinnings of intra-tumor heterogeneity in progression and therapeutic resistance are however largely unknown. Single-cell RNA-sequencing (scRNA-seq) has revealed significant inter- and intra-tumoral molecular heterogeneity in Glioblastoma (GBM), an aggressive brain tumor that is obstinate to most therapies. However, this ...
Prenatal acrylamide exposure, its transcriptomic signature and interaction with genetic polymorphsims: associations with perinatal and postnatal development Hasselt University
Since 2002, we know that many heat-treated foods contain acrylamide, which means that everybody is exposed to this compound. In rodents, acrylamide causes cancer and toxic effects to the nervous, developmental and reproductive system. It is still unclear whether acrylamide at dietary doses causes adverse health effects in humans. There are concerns that it may cause adverse effects on fetal growth and neurotoxic effects in children and this ...
X-SENSE3 - Smart environmental sensing through a self-powered, compact and versatile sensing platform using (plant-) Microbial Fuel Cells: a cross-disciplinary approach (co-financing EFRO-project Digital Acceleration DIGVER1181 - UHasselt/LRM/IMEC) Hasselt University
The overarching theme of the co-financing EFRO-project DIGVER1181, with partners UHasselt / X-LAB, LRM and IMEC, is digital acceleration and cross-over of disciplines. The present project is therefore situated at the crossroads of two 'big challenges', namely digital transformation (eg Internet of Things, Smart Cities...) and climate/ environment/energy-challenges. The general objective is 'smart environmental sensing' (city, nature...) through ...
The impact of nutrient homeostasis, the oxidative balance, the cell cycle and their interplay on cadmium-induced plant growth restriction. Hasselt University
Cadmium (Cd) is a major soil pollutant that reduces plant growth and hence crop yield, but also poses a risk to human health, mainly via accumulation into the food chain. As a consequence, Cd polluted soils are not used in an optimal way. The goal of this project is to gain knowledge on the processes contributing to this reduced plant growth, trying to find a way to reverse or compensate this. Three processes important for optimal plant growth ...
High-dose locoregional chemotherapy in the lung: towards a less invasive percutaneous technique. University of Antwerp
Surgical resection of lung metastases is a widely accepted procedure but due to local and distant recurrences reported 5-year survival rates are only 30 to 40%. Reoperations are feasible but often patients become inoperable due to insufficient pulmonary reserve and for this reason new treatment modalities are being investigated. The maximal dose of intravenous chemotherapy is limited due to systemic side-effects, mainly haematological. As is the ...
Plant adaptability underchronic low dose gamma exposure Hasselt University
Life is constantly exposed to some form of radiation. However, with the increase of anthropogenic activities and accidents this can be significantly increased. The accident at Chernobyl or Fukushima, for example, in which large areas were contaminated with radiation. Yet nature persists in these dangerous zones, which has sparked the discussion on a possible adaptability to radiation. Already some potential signs have been found in plants within ...
Unravelling uranium uptake mechanisms in Arabidopsis thaliana Hasselt University
Uranium (U) is a radionuclide and heavy metal that naturally occurs, in relatively low concentrations, in soils and in aquatic environments. Due to anthropogenic activities, such as U mining and the phosphate industry, concentrations have locally risen to concentrations that may have an ecological impact. A lot is known about U toxicity in plants, yet little is known about the uptake mechanisms. This information, however, could prove useful to ...