Projects
Development and mechanism of action of novel inhibitors of rabies virus replication. KU Leuven
Rabies viurs infection causes encephalomyelitis in humans with a nearly 100% case fatality rate. Current strategies of post-exposure prophylaxis treatment(PEP) are highly effective and involve vaccination together with infiltration of the wound with anti-rabies immunoglobulins(RIG's). Each year ~60,000 people succumb because of rabies and the societal cost worldwide is estimated to be in excess of US$6 billion. However, effective antivirals ...
Sludge concentrations in the water column and the relation with human intervention in the Scheldt estuary. University of Antwerp
Study of microbial interaction networks among heterotrophic bacteria from river waters KU Leuven
Rivers represent aquatic ecosystems among the most suffering from anthropogenic activities, by their regular and important exposure to massive inputs of organic matter and chemical pollutants. Bacteria play a key role in rivers’ ‘self-purification’ by their action of mineralization of organic matter and export of carbon to the atmosphere, and besides they form an important trophic link as they are located at the bottom of the food chain. ...
Influence of nutrient-enriched groundwater on seepage-dependent ecosystems University of Antwerp
Hyperendemic M. tuberculosis from a hypertemporal genomic perspective (HyperMTB). University of Antwerp
Characterization of the parasite-related factors associated with the visceralization capacity of Leishmania donovani. University of Antwerp
Improved respiratory syncytial virus (rsv) vaccines based on glycan modification of the viral fusion (f) protein. University of Antwerp
Invasive salmonellosis in the Democratic Republic of the Congo KU Leuven
Invasive salmonellosis comprise deep-seated infections with Salmonella Typhi as well as with the Non-Typhoidal Salmonella (NTS), which are the main cause of bloodstream infections in sub-Saharan Africa. Invasive salmonellosis is associated with a high case fatality rate (up to 25% for NTS bloodstream infections in children) and increasing resistance to multiple antibiotics. Although recognized as a public health problem, their exact incidence ...