TIE receptors as molecular switches between pro-angiogenic or vascular normalizing effects of macrophages. Ghent University
Angiogenesis, the process of blood vessel development, is an important mechanism in health and
disease. Angiogenesis is extensively being studied as a therapeutic target in conditions where
aberrant blood vessel growth worsens the clinical outcome, such as in atherosclerotic plaque
formation. However, angiogenesis is also being studied as a therapeutic tool to resupply ischemic
tissue with blood vessels. A good knowledge ...