Visceral hypersensitivity after a bacterial gastroenteritis: a role for neuro-immune interaction? KU Leuven
Increased visceral pain perception or visceral hypersensitivity is considered an important pathophysiological mechanism explaining the clinical presentation of irritable bowel syndrome (IBS) after an episode of bacterial gastroenteritis. Recent studies support a key role for persistent microscopic mucosal inflammation and an influx of mast cells in the development of visceral hypersensitivity. However, it is unknown why only 10-25% of ...