Neurotoxicity of anesthetics in the developing brain of fetal rabbits and neuroprotective agents KU Leuven
There is increasing concern that exposure of the developing brain to anesthetics might be associated with impaired neurodevelopmental outcome in children undergoing surgery during their early life or even before birth.
Preclinical experiments in rodents and non-human primates have consistently shown that virtually all commonly used anesthetics cause apoptotic neurodegeneration that result in persisting neurocognitive impairment. In ...