Projects
Prevention of glucose toxicity prevents renal damage during critical illness: mechanistic studies in a rabbit model. KU Leuven
The development of intensive care medicine allowed patients to survive life-threatening conditions thanks to sophisticated mechanical and/or pharmacological support. However, a considerable fraction of patients do not recover their acute critical illness within a few days, but enter astate of prolonged critical illness. Prolonged critically ill patients have a high risk of death, which is most often due to a sustained failure of multiple vital ...
The importance of endothelial progenitor in sepsis: do they have a role to play in diagnosis, pathophysiology and prognosis of sepsis related organ failure. University of Antwerp
Vaccine & Infectious Disease Institute (VAXINFECTIO), Translational Pathophysiological Research (TPR), Laboratory Experimental Medicine and Pediatrics (LEMP)
Wij willen de rol van EPCs onderzoeken als diagnostisch hulpmiddel en biomerker van endotheliale dysfunctie in sepsis. A. Is er een correlatie tussen het aantal EPCs en de progressie, de graad van orgaandysfunctie, "disease progression" en prognose in sepsis ? B. Is er een correlatie tussen de het aantal EPCs en de graad van endotheliale dysfunctie zoals geobjectiveerd door middel van zowel biomerkers van endotheeldysfunctie in het perifere ...
Optimization and implementation of a control system aiming the normalization of glycemia in critically ill patients. KU Leuven
ESAT - STADIUS, Stadius Centre for Dynamical Systems, Signal Processing and Data Analytics, Laboratory of Intensive Care Medicine
Critically ill patients, typically admitted to the intensive care unit, show hyperglycemia and insulin resistance resulting in adverse outcomes. It has been previously shown that strict blood glucose control (between 80 and 110 mg/dl) results in an important reduction in mortality and morbidity. Current therapy requires a manual and rigorous administration of insulin and could, therefore, be replaced by a semi- or fully-automatic blood glucose ...