Projects
Optimizing brain perfusion in critical illness and acute brain injury: bringing computer models to the bedside. KU Leuven
Critical Care Medicine is a relatively young and high-tech branch in modern medicine that combines clinical skills, powerful drugs and sophisticated mechanical devices to support the function of vital organs. This allows patients to survive a variety of previously lethal insults such asmultiple trauma, extensive surgery or severe infections. Despite this dedicated care, mortality among critically ill patients who require intensive care for ...
Recovery from critical illness: role of autophagy and epigenetics. KU Leuven
The development of critical care medicine over the last 50 years allowed patients to survive acute life-threatening conditions. Whereas most of these patients recover within a few days, a substantial number of critically ill patients develop multiple organ failure (MOF), which prolongs the dependency on intensive care and increases health care costs. Despite major advances in intensive medical care, MOF is still a leading cause of morbidity ...
Clinical prediction models in intensive care. KU Leuven
Metabolic stress, mitochondrial dynamics and organ failure during critical illness: towards a novel therapeutic intervention. KU Leuven
Insulin and the immune response to critical illness KU Leuven
In order to survive, the human body has to protect itself against the continuous threat of external aggressions, as well as against endogenous stress caused by ageing, dysfunctional, mutated or damaged cells. In conditions of extreme stress, the organism will either recover quickly and survive, or will succumb. Thanks to innovations in intensive care medicine, patients are nowadays able to survive such acute life-threatening conditions. ...