Projects
PIGF inhibition as a new therapeutic approach to filtration failure after glaucoma filtration surgery. KU Leuven
New therapeutic approaches to filtration failure after glaucoma surgery.
Research to establish specific product and process characteristics from an innovative technological process to produce inserts loaded with peptides/proteins. University of Antwerp
Development and evaluation of pharmaceutical forms loaded with a therapeutic peptide used for ocular purposes University of Antwerp
Characterizing the limits in low vision patients by exploring potential beneficial effects of visual noise. KU Leuven
De rol van MMP-2 en MMP-14 in glaucoom: implicaties voor celtherapie? KU Leuven
Matrix metalloproteinases (MMPs), a family of Zn2+-dependent proteases, were originally named after their ability to cleave and remodel the extracellular matrix (ECM), however, their substrate repertoire has proven to be much broader, comprising other proteinases, growth factors, signaling molecules, cell surface receptors, and even intracellular targets. By proteolytic cleavage, MMPs modify the structure and activity of these substrates, and ...
ROCK inhibitors as novel antifibrotic strategy for glaucoma surgery. KU Leuven
Glaucoma is a chronic optic neuropathy which is characterized by the loss of retinal ganglion cells, resulting in irreversible visual field loss. It is the most important cause of irreversible blindness worldwide and with aging of the population the number of glaucoma patients is still expanding. Mostly the appearance of this disease is correlated with an increased intraocular pressure (IOP), due to an imbalance between aqueous humor ...