Projects
Pathophysiology of epileptic encephalopathies: insights from genetics in patients and in vivo modelling in zebrafish and fruit flies. University of Antwerp
Amyloid β and sleep problems, a neurotoxic pas de deux during aging? University of Antwerp
Dysfunctional endocytosis in epilepsy. University of Antwerp
Role of PDE10A in Alcohol Addiction: combining multimodal neuroimaging techniques and advanced learning strategies to predict relapse propensity KU Leuven
Alcohol addiction is the most common complex psychiatric disorders affecting society. However, the exact signaling pathways and mechanisms underlying the development of alcohol addiction and the relapse propensity are still unclear. Phosphodiesterase 10A (PDE10A) is a dual substrate enzyme highly enriched in striatal medium spiny neurons, where it regulates intracellular signaling processes including dopaminergic transmission. PDE10A is ...
Training postural and gait balance control in children with Cerebral Palsy: associations between brain structural metrics and motor behavior KU Leuven
When an injury occurs to the developing brain, as in Cerebral Palsy (CP), children experience deficits in motor control. Poor postural control is a primary deficit in CP with a large impact on a child’s daily life, since it is crucial for gait and, thus, greatly affects the risk of falls. To improve their quality of life, adequate treatment is essential. However, the success of treatment greatly depends on the knowledge of the underlying ...