Parental Pesticide and Offspring Epigenome study (PaPOE): Assessment of pesticides exposure and association with cancer among farmers, pregnant women and their offspring KU Leuven
Environmental toxicants, like pesticides, can alter epigenetic regulatory features such as DNA methylation. The PaPOE (Parental Pesticides and Offspring Epigenome) study aims to investigate whether pesticides exposure could induce epigenetic changes associated with an increase in cancer risk. We will, in fact be, investigating how (re)programming in early life can have long-term consequences for later health outcomes through DNA methylation ...