Investigations on selected natural product classes as inhibitors of Advanced Glycation Endproducts (AGEs) and modulators of autophagy University of Antwerp
During previous investigations in the host laboratory it has been found that several classes of natural products, i.e. polymethoxy-flavones, biflavonoids, xanthones and quinazoline alkaloids, exhibited AGEs inhibiting properties. AGEs (or Advanced Glycation Endproducts) are implicated in many age-related chronic diseases and in protein ageing, and are associated with diabeticcomplications, atherosclerosis, neurodegenerative diseases, cancer and ...