A study of the impact of stopping rules on conventional estimation with probabilistic and approach theoretic techniques University of Antwerp
In a sequential trial, the data collector is allowed to take intermediate looks at the data. After each intermediate look, he can decide, based on the data observed so far and a prescribed stopping rule, if the trial is stopped or continued. Stopping a trial early is potentially beneficial for economic and ethical reasons in e.g. a clinical study. The existing literature on sequential trials has reported that simple conventional estimators, such ...