Projects
Creating structural and physico-chemical control to enhance properties of hybrid periodic mesoporous metal phophonates. Hasselt University
Metal oxalates in 15-16th century Netherlandish oil paintings (METOX) University of Antwerp
Environmental analysis and the added value of electrochemistry for the detection of environmentally important molecules. University of Antwerp
Bisphenol A alternatives: transfer from food contact materials, fate and human exposure. University of Antwerp
3D dynamic super-resolution imaging of bacterial lysis. KU Leuven
Fluorescence microscopy allows researchers to observe dynamic processes in live-cells. Unfortunately, the size of bacterial cells (~1 μm), among others, is close to the resolving power of an optical microscope, known as the diffraction-limit. Therefore, while the general shape of bacteria can be seen, their sub-cellular details cannot be resolved. Particularly, observing the modifications induced by antibiotics on a live bacterium is strongly ...
Support for ongoing restoration and researchprojecten of the Royal Museum of Fine Art Artwerp by means of chemical analyses and imaging methods (scanners) University of Antwerp
Multicomponent/cascade cyclization strategies (MCCS) for the synthesis of bioactive natural products and analogues KU Leuven
This thesis describes the application of multicomponent/cascade cyclization strategies (MCCS) for the synthesis of bioactive natural products and the main scaffolds exist in natural products. The research is based on the A3 coupling, and post-Ugi reactions developed previously in our laboratory.
Chapter 1 gives an introduction to multicomponent reactions and cascade reactions. Giving the conception of the MCCS and highlighting the ...
Improving late stage functionalization of molecular scaffolds via CH activation - implementation of ultrasound and flow chemistry techniques KU Leuven
Sulfur is a ubiquitous element in physiologically active small molecules. With 259 unique FDA-approved structures, it represents more marketed therapeutics than any other third row element. Almost half of this figure comprises the sulfur atom in an oxygenated state, and this fraction spans over six different product classes. The synthesis and usage of high-oxidation-state sulfur species form the centerpiece of this thesis, on the one hand ...