The study of the possible interactions between human Mas-related G Protein-coupled receptors. University of Antwerp
Mas-related G-Protein coupled receptors (Mrgpr's) have a putative role in sensory processes, including itch and pain. Previous studies on Mrgpr's in intestinal inflammatory conditions revealed marked expressional changes in them, specifically in sensory neurons of enteric nervous system (ENS). The fact that most of Mrgpr's are still classified as orphan, has hampered the study of their functions and regulatory mechanisms. This project develops ...