Direct C(sp3)-H activation: Transition metal-catalyzed functionalization of saturated cyclic amines. University of Antwerp
This research project aims to develop direct transition metalcatalyzed alkylations of C(sp3)–H bonds in saturated nitrogen-based heterocycles, with a particular focus on compatibility with a very broad range of functional groups, regioselectivity and stereoselectivity. Towards this goal, insertion reactions with substituted alkenes featuring a variety of functional groups will be explored. The development of such a technology offers an important ...