The discovery of efficient technologies enabling the use of CO2 as a starting material for chemical synthesis is one of the most significant challenges of our time. They could serve the dual purpose of reducing CO2 emissions and producing value-added chem
Chemical reactor design and optimization based on insights and data on a molecular level can become reality in the coming decade. Multiscale simulations including all elementary reaction steps in a full microkinetic model, with information on catalyst str
This proposal aims to provide a thorough understanding of the surface chemistry and physics during atomic layer deposition (ALD) of cobalt and nickel for applications in microelectronics and catalysis. In microelectronics, ALD of high quality, continuous
Although an increasing number of analytical techniques and methods are becoming available for the detection, identification and quantification of nanoparticles (NPs) during the nanomaterial production process, their application is still a major challenge
The 2018 Nobel Prize in Chemistry was awarded to work on U+2018directed evolutionU+2019. The latter is not a new theory or discovery, but a technique to let natural selection shape proteins for us. Advances such as these are often claimed to indicate a bigger shift
Peptide Hydrogels are swollen networks of self-assembled peptide nanofibers that contain large
amounts of water. An important characteristic of such hydrogels is that they can be aspirated and
injected through a standard needle. Recently, we developed such peptide hydrogels that extended
the pain killing effect of morphine form several hours up to 3-4 days. However, further extension of
the sustained release time is ...
De on-site en zeer selectieve detectie van cocaïne en andere belangrijke doelanalyten zoals
antibioticaresiduen in afvalwater blijven een uitdagend onderzoeksgebied. In dit project willen we dat
beter begrijpen en uiteindelijk verbeteren van analytische detectiesystemen die kort DNA gebruiken
sequenties voor selectieve herkenning van interessante moleculen - aptamers genaamd - gevolgd door de
generatie van elektrische ...
Hydrogels are three-dimensional networks of cross-linked hydrophilic copolymers. Their viscoelastic properties can be tailored by adjusting the chemical composition of the copolymers which build up the hydrogel. Poly(oxazoline)s (POx) are a class of low dispersity polymers. The poly(2-ethyl-2-oxazoline) is biocompatible, stealthy and non-toxic, which makes this hydrophilic polymer, as well as POx hydrogels interesting for various biomedical ...
Developing drugs is a time- and cost-intensive process. During drug development, different phasesare required for a drug to finally reach the market. During the discovery and development phase, thousands of compounds are synthesized, of which the most appropriate reach the preclinical phase. During this phase, in vitro and in vivo tests are performed in an attempt to track toxicity. Due to ethical as well as economic constraints, there is a ...
In this project we will study the crystallization process of pharmaceutical compounds using state-ofthe-
art nonlinear optical scattering techniques, combined with more traditional linear scattering and
x-ray scattering techniques. The proposed techniques provide complementary information about
different stages of the process, from aggregation and nucleation to subsequent growth. This opens a
window into the fundamental ...