Projects
osMID – on-site multiscreening of illicit drugs. University of Antwerp
Towards a targeted optimization of electrocatalysts by combining electrosynthesis with in-situ electron paramagnetic resonance. University of Antwerp
Electrochemical (bio)sensor development. University of Antwerp
Multicomponent/cascade cyclization strategies (MCCS) for the synthesis of bioactive natural products and analogues KU Leuven
This thesis describes the application of multicomponent/cascade cyclization strategies (MCCS) for the synthesis of bioactive natural products and the main scaffolds exist in natural products. The research is based on the A3 coupling, and post-Ugi reactions developed previously in our laboratory.
Chapter 1 gives an introduction to multicomponent reactions and cascade reactions. Giving the conception of the MCCS and highlighting the ...
Improving late stage functionalization of molecular scaffolds via CH activation - implementation of ultrasound and flow chemistry techniques KU Leuven
Sulfur is a ubiquitous element in physiologically active small molecules. With 259 unique FDA-approved structures, it represents more marketed therapeutics than any other third row element. Almost half of this figure comprises the sulfur atom in an oxygenated state, and this fraction spans over six different product classes. The synthesis and usage of high-oxidation-state sulfur species form the centerpiece of this thesis, on the one hand ...
The impact of the electrocatalytic properties of Cu/Ag core-shell nanoparticles for the reduction of CO2 in an electrochemical flow microreactor. University of Antwerp
Exploring the chemistry of N-hydroxypyrazinones KU Leuven
Although industrial processes readily use reactive and dangerous gases as platform chemicals, a different picture is seen in lab-scale synthesis. The difficult-to-handle nature of gaseous reagents in combination with stringent safety requirements have posed a significant barrier for research scientists to conduct chemical reactions with gases on a regular basis.
In 2011, the Skrydstrup group launched the two-chamber reactor as a safe ...