Patents

The invention relates to a novel compound for the treatment and prophylaxis of a disease, especially a bacterial infectious disease, for reducing pathogen virulence and promoting host-induced clearance of infection and/or sensitizing bacteria to antibiotic treatment, a method for preparing said compound, a pharmaceutical composition comprising said compound, and to a method for the treatment and/or prophylaxis of a disease, preferably a bacterial infectious disease.

The present application relates to a metal-free photocatalytic method and system for converting polystyrene into benzoic acid, using a metal free catalytic system. In particular, the method and system described herein allow to generate benzoic acid directly from polystyrene, such as originating from plastic waste, by irradiating polystyrene dissolved in a solvent with UV light, in the presence of oxygen and a metal free activating compound, such as an acid, a succinimide derivative, or a bromide salt of an alkali metal or alkaline earth metal.

In a first aspect, the present invention relates to a second-order nonlinear optical device, comprising (i) an active layer and (ii) an electric field generator. The active layer comprises (ia) a matrix material, and (ib) second-order nonlinear optical chromophores dispersed in the matrix material. Each chromophore has a conjugated system comprising at least a first nitrogen atom connected to a second nitrogen atom via a conjugated path and a positive charge localized on one of the nitrogen atoms. Moreover, the chromophore is switchable between a first state in which the positive charge is ...

In a first aspect, the present invention relates to a second-order nonlinear optical device, comprising (i) an active layer and (ii) an electric field generator. The active layer comprises (ia) a matrix material, and (ib) second-order nonlinear optical chromophores dispersed in the matrix material. Each chromophore has a conjugated system comprising at least a first nitrogen atom connected to a second nitrogen atom via a conjugated path and a positive charge localized on one of the nitrogen atoms. Moreover, the chromophore is switchable between a first state in which the positive charge is ...

The present invention relates to the field of organic synthesis, and in particular, the present invention pertains to a process for preparing a levulinic acid or salt thereof, or levulinate.

The present invention relates to a sprayable formulation comprising live and/or stable bacteria and methods for making such sprayable formulation; in particular in the form of a liquid spray. The invention further relates to the use of this sprayable formulation in human or veterinarian medicine and the use of this sprayable formulation for the prevention and/or treatment of respiratory diseases. The invention further provides methods for the prevention and/or treatment of respiratory diseases.

The present invention relates to the field of polyurethane recycling and pertains to a method of recycling of a polyurethane, comprising a first alcoholysis step and a further thermolysis step. By means of the method according to the present invention, it is possible to recover both the polyols and isocyanates from said polyurethane.

The present invention relates to a compound of formula (I) or a tautomer thereof, wherein R1, R2, R3, R4 and R5, have the same meaning as that defined in the claims and the description. The present invention also relates to compositions, in particular pharmaceuticals, comprising such compounds, and to uses of such compounds and compositions for the prevention and/or treatment of epilepsy and/or neurodegenerative diseases.

The present disclosure relates to novel compounds, to said compounds for use as a medicine, more in particular for the prevention or treatment of diseases mediated by activity of YAP/TAZ-TEAD transcription, yet more in particular for the prevention or treatment of cancer or fibrosis. The present disclosure also relates to a method for the prevention or treatment of said diseases comprising the use of the novel compounds.

The invention relates to a process for preparing cyclic esters by means of a transesterification reaction in the gas phase, comprising the steps of: (i) vaporizing a liquid solution of alpha-hydroxy esters, (ii) passing the ester vapors through a reaction zone containing a solid catalyst and (iii) recovering the cyclic esters from the gaseous product stream; and wherein the solid catalyst comprises at least one metal of titanium (Ti) and Zirconium (Zr), and a SiO2 support, and wherein said metal is chemically bound to the SiO2 support through M-O-Si chemical bonds.