Title Promoter Affiliations Abstract "A stAPP for a better health." "Christophe Delecluse" "Physical Activity, Sports & Health Research Group" "Aim:In this project we want to measure sedentary behavior and make people aware of it. Consequently we want to stimulate a change in this behavior by means of an innovative and amusing application on a smartphone. Subjects:We aim to decrease the sedentary behavior in the home environment and leisure time of people between 19 and 59 years of age. Design:This project is a collaboration between physical activity counselors, staff of the Lokaal Gezondheidsoverleg (Logo), psychologists and engineers. Phase 1: The app will be designed, validated and an intervention study will be set up. By means of a permanent interaction between users, researchers, designers and field workers, the app and its tools will be designed, optimized and refined. Consequently the app will be validated by a representative group of users. Subsequently, in a controlled intervention study we will study the impact of the app on the sedentary behavior of the users. Phase 2: The app will be tested in a sample in 2 pilot towns in the region of Logo Oost-Brabant by means of interactive workshops and/or information sessions. This implementation is in collaboration with Logo Oost-Brabant." "One stApp for a better health." "Vero Vanden Abeele" "Computer Science Technology, Group T Leuven Campus, Physical Activity, Sports & Health Research Group" "The objective of this project is to reduce sedentary behavior among adults, in the home environment. Sedentary behavior is defined as prolonged sitting (over 30 minutes), with damaging consequences for ones personal health. By means of an application on a smartphone and associated sensors, we will measure the sedentary level of the user, and inform him or her. The smartphone application will provide a rich user experience, and based on self-determination theory, stimulate him or her to stop sitting." "Targeting the leukemic cancer stam cell in early T-cell precursor Acute Lymphoblastic Leukemia (ETP-ALL)" "Pieter Van Vlierberghe" "Department of Biomolecular Medicine, Department of Pediatrics and medical genetics" "The abstract for ""Targeting the leukemic cancer stam cell in early T-cell precursor Acute Lymphoblastic Leukemia (ETP-ALL)                "" is missing. Please contact the promotor for more information." "Shame and sustainability in fashion: A new integrated perspective on the role of shame in the industrial fashion system and in the formation of fashion’s communities of honor in the 21st century" "Giselinde Kuipers" "Centre for Sociological Research" "Fashion revolves around shame. The evocation of time shame, the unpleasant feeling of being outmoded, is central to fashion. This project analyzes time shame as the basis of the emotional regimes of today's industrial fashion system by studying how this emotion aids the fashion industry in creating boundaries between industry and consumers, and between groups of consumers. The 21st century witnessed the rise of ‘fashion's honor communities’ that turn the mirror of shame towards industrial fashion in campaigning for sustainability. The developing honor communities thrive on ‘moral shame’. Through 3 qualitative studies of the self-directed and vicarious moral shame circulating in these communities the project theorizes the concept of ‘fashion's honor communities’, maps their formation, describes the affects fortifying their cultural narratives of moral advancement and analyzes the pragmatic and ethical difficulties that limit their transformation into mature communities of honor. Next, the project unearths how the fashion industry responds to moral shame in 3 qualitative studies of fashion media and education. Thus, the project develops a new integrated perspective, connecting previously isolated traditions in fashion studies, that offer an empirically-grounded, original contribution to understanding sustainability in fashion studies and the role of normative emotions in shaping new cultural narratives that may morally advance the industrial fashion system." "Perturbing tumor-associated macrophage (TAM) equilibrium using GPNMB/CD206 nanobodies and nanoparticles in breast cancer." "Jan Gettemans" "Department of Biomolecular Medicine" "Nanobodies are highly attractive to promote better active nanocarrier targeting, while M2-TAMs (tumor-associated macrophages) dominate the tumor microenvironment (TME) resulting in a worse treatment of breast cancer. Hence, there is a clear need to develop novel strategies to perturb TAM equilibrium. This project will use GPNMB/CD206-targeted nanobodies and nanoparticles to reveal the specific pathways for M2-TAMs re-education." "Theology, Law, and Ethics in Late Medieval Ḥanbalīsm: The Intellectual Legacy of Shams al-Dīn Ibn Mufliḥ (d. 763/1362)" "Arjan Post" "Arabic Studies, Leuven" "The late-Ḥanbalī polymath Ibn Mufliḥ (d. 763/1362) stands as a unique figure within the Ḥanbalī school. His works in law and jurisprudence would propel him as an authoritative figure among later scholars attempting to determine relied-upon positions in the school. His work in legal theory would further determine the school's convention and approach within the science. Alongside these works, his seminal study of ethics would serve as a catalyst for numerous later works in the field, all independent of traditional law manuals. At the same time, Ibn Mufliḥ was a devoted pupil of Ibn Taymiyya, preserving and relating his legal opinions throughout his works. Whereas modern scholarship notes various areas of conflict between the school and Ibn Taymiyya's divergent views, Ibn Mufliḥ's role as a central authority on both, and who apparently attempts to harmonize the two, calls to question the extent of this separation." "Tension-sensitive seams for tracking body movements" "Sheilla Odhiambo" "FTILab+, HOGENT" "The concept of strain sensing seams that can monitor body movement was developed and demonstrated in the framework of the project: Sensing and Actuating Functional Seams Applying Hybrid Yarns for the FashionTech Industry (Project nr. HBC.2019.2679 (478) (CORNET-2020). A controller unit that houses the processor, battery, and wireless communication was also developed within the project framework. This was integrated within a sports clothing prototype to present a stand-alone unit of smart textile clothing. There is need to bring this technology closer to the user by further working on this development. The prototype needs further developments and evaluation to improve on the design, response, accuracy, and stability of the system, and the prototype tested under real or real-like conditions. Thus this research will further improve the strain sensing system: seams, interconnections, the controller unit, the software, and the overall smart clothing prototype. The sensing system will be evaluated under various conditions. The sensors will be produced on appropriate base fabrics for the cyclist garments and the sensor positions designed and placed accurately in the required positions according to the size of the garment. The interconnection of the controller to the sensors will be decided on based on suitability, and stability to the functioning of the system. The controller unit will be made smaller and compact and made easy to use “ plug and play. The software will be improved further for quick response and stability. Finally, the whole system has to be evaluated in terms of stability, reliability, durability, and reproducibility among other desirable aspects. The knowledge gained will be shared through various channels to the industries and the public at large, including updates to students’ curricula. This project results will be a big step towards full integration of the sensing systems within the garment thus guaranteeing user comfort and productivity. The sensors will be made by well-established processes and with available materials. Thus companies may pick up this technology easily. Moreover, these strain sensors may be potentially easier to connect to the readout and processing electronic components and hence may be easily disassembled and disposed of at the end of the life of the product if fabric recycling is required. Their integration into the garments towards the end of the production process of the garment, offers definite advantages in terms of flexibility and production costs." "Predicting impending beta cell loss and dysglycemia in asymptomatic type 1 diabetes - Validation of minimally invasive markers against the hyperglycemic clamp test." "Bart Keymeulen" "Pathology/molecular and cellular medicine" "We aim to monitor functional beta cell mass and insulin action using the gold standard hyperglycemic clamp test (HCT) in asymptomatic type 1 diabetes (T1D) in relation to known determinants of disease progression. This may help to unravel the heterogeneous nature of pre-T1D. The majority of beta cell loss is hypothesized to occur within 2 years prior to diagnosis. Simultaneously, promising minimally invasive techniques (continuous glucose monitoring [CGM]-derived indices of glycemic variability, proinsulin, proinsulin:C-peptide ratio), will be validated against HCT in order to derive objective criteria for identifying individuals at high risk of impending major beta cell loss and clinical onset, and to develop an affordable simple screening for large scale application. Using the capacity of a nationwide clinical network to identify multiple autoantibody-positive (mAAb+) firstdegree relatives (FDRs) of T1D patients, normo- or dysglycemic mAAb+ FDRs (5-39 years) are enrolled and followed twice a year by oral glucose tolerance tests, CGM and HCT for at least 2 years or to onset. Time-to-event analysis and machine learning techniques will be used to identify best predictors of progression to dysglycemia or clinical onset. The results may facilitate early diagnosis, avoidance of ketoacidosis, development of new prevention trials in pre-T1D, and might serve as a first step in the implementation of a cost-effective population-wide screening and prevention strategy long-term." "SmartSeam - Sensory and Actuating Functional Seams Applying Hybrid Yarns for the FashionTech Industry" "Alexandra De Raeve" "FTILab+, Creamoda, Forschungskuratorium Textil e. V., Hochschule Niederrhein" "The main objective of the project was to develop smart, functional seams - sensors and/or actuators- for application in sports (strain-sensitive seams), in underwear (moisture-sensitive seams), and in personal protective clothing (luminous seams). The methodology includes defining input material, yarn structure, seam design and specifications, and finally defining the specifications of demonstrators (WP1). In addition, there was the design and development of conductive hybrid yarns by hollow spindle and ring spinning technologies and selection of commercially available conductive (hybrid) yarns for use in seams under (WP2), development of sets of different types of smartseams using the developed conductive (hybrid) yarns by sewing technology under (WP3), creation of the functional garment demonstrators (WP4), as well as characterisation and evaluation of yarns, seams and final demonstrators under (WP5). Following results were obtained: - knowledge on the production of electrically conductive hybrid yarns for sewing and embroidery and guidelines for the industry on spinning conductive hybrid yarns. Specifically, 10 different types of conductive hybrid yarns were developed using hollow spindle spinning technology and subsequently characterised. - Knowledge of test methods to characterise the conductive hybrid yarns - Knowledge of design and development of strain-sensitive seams, light-emitting seams and moisture-sensitive seams - Knowledge of test methods to characterise sensory seams (i.e. sewability, reproducibility, functionality and stability) and comfort of garments with built-in functionalities - Knowledge on coating conductive yarns to maintain functionality - Identification of strengths and weaknesses related to the design and development of conductive hybrid yarns, sensing seams and smart garment products. Finally, 3 demonstrators were developed, produced and characterised: a vest with active light-emitting seams, a sports shirt with capacitive or resistive sensor seams to measure upper body movement, and an undergarment to measure humidity and body temperature." "The house's honour (ghar kī 'izzat): a study of shame in north Indian children and women's periodical and didactic literature (1870s-1940s)" "Eva De Clercq" "Department of Languages and Cultures" "A crucial step towards understanding and explaining better socio-cultural norms and historical practices and thus facilitating intercultural dialogue is the consideration of affects. Focusing on a critical moment of the history of India, which saw the refashioning of social norms of behaviour, this project explores the most social emotion, shame, and its expressions in Hindi and Urdu-language literature for women and children to shed light on how subaltern actors navigated their feelings and their community and religious identities, and participated in the making of modern South Asia. Drawing cross-language and cross-religious comparisons, this project will contribute to the growing and innovative field of the history of emotions."