Researcher
Zeger Debyser
- Disciplines:Laboratory medicine, Microbiology, Systems biology, Biomaterials engineering, Biological system engineering, Biomechanical engineering, Other (bio)medical engineering, Environmental engineering and biotechnology, Industrial biotechnology, Other biotechnology, bio-engineering and biosystem engineering
Affiliations
- Molecular Virology and Gene Therapy (Division)
Responsible
From1 Jan 2012 → Today - Molecular Virology and Gene Therapy (Division)
Member
From1 Jan 2013 → Today - Faculty of Medicine, Kulak Kortrijk Campus (Faculty)
Member
From1 Oct 2003 → 29 Feb 2008 - Faculty of Medicine (Faculty)
Member
From1 Oct 1999 → 30 Sep 2003
Projects
1 - 10 of 77
- Bottom-up manufacturing of artificial anti-tumor T cellsFrom1 Feb 2024 → TodayFunding: HORIZON.3.1 - European Innovation Council (EIC)
- DEVELOPMENT OF LINE-1 INHIBITORSFrom1 Oct 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Design of targeted degraders of LEDGF/p75 with applications as anticancer agentsFrom25 Sep 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- HIV Latency and the epigenetic landscape: studying individual patients for developing HIV cure strategiesFrom1 Mar 2023 → TodayFunding: Geopolitical funding in general (R&D collaboration with Central and Eastern Europe
- Towards a functional cure strategy of HIV infection: Single virus imaging to study the impact of HIV nuclear import and integration on transcription and latencyFrom1 Sep 2022 → TodayFunding: FWO Strategic Basic Research Grant
- INNOVATIVE THERAPIES FOR LINE-1 DISEASEFrom1 May 2022 → TodayFunding: BOF - various
- Single virus live imaging of HIV nuclear import and integrationFrom1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- Targeting LEDGF/p75 for Mixed Lineage Leukemia and chemoresistant malignanciesFrom16 Oct 2021 → TodayFunding: FWO Strategic Basic Research Grant
- Role of the epigenetic reader LEDGF/p75 in health and diseaseFrom1 Oct 2021 → TodayFunding: Fund Recuperation Fiscal Exemption, BOF - projects
- Role of the interaction between LEDGF and MeCP2 in LINE-1 retrotransposition in the brainFrom1 Sep 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
Publications
261 - 270 of 305
- High Resolution profiling of the LEDGF/p75 chromatin interaction(2009)
Authors: Jan De Rijck, Koen Bartholomeeusen, Hugo Ceulemans, Zeger Debyser, Rik Gijsbers
Pages: 6135 - 6147 - Microwave-assisted palladium-catalyzed heterogeneous vinylation of 2(1H)-pyridones(2009)
Authors: Brajendra Kumar Singh, Claudia Cavalluzzo, Marc De Maeyer, Zeger Debyser, Erik Van der Eycken
Pages: 4589 - 4592 - Type 2 Cannabinoid Receptor Based Reporter Gene Constructs for Brain PET Imaging(2009)
Authors: Caroline Vandeputte, Nele Evens, Jaan Toelen, C Deroose, Zeger Debyser, Alfons Verbruggen, Guy Bormans, Veerle Baekelandt, Koen Van Laere
Pages: S239 - S239 - Highly efficient multicistronic lentivectors with peptide 2A sequences(2009)
Authors: Abdelilah Ibrahimi, Greetje Vande Velde, Veerle Reumers, Jaan Toelen, Caroline Vandeputte, Christophe Deroose, Guy Bormans, Veerle Baekelandt, Zeger Debyser, Rik Gijsbers
Pages: 845 - 860 - Pharmacophore-based discovery of small-molecule inhibitors of protein-protein interactions between HIV-1 integrase and cellular cofactor LEDGF/p75(2009)
Authors: Frauke Christ, Zeger Debyser
Pages: 1311 - 1316 - Microwave-Assisted Silver(I)-Mediated Selective O-Alkylation of Aromatic Imidate Systems(2009)
Authors: Brajendra Kumar Singh, Claudia Cavalluzzo, Marc De Maeyer, Zeger Debyser, Erik Van der Eycken
Pages: 2725 - 2728 - Exploration of novel hiobarbituric acid-, rhodanine- and thiohydantoin-based HIV-1 integrase inhibitors(2009)
Authors: Frauke Christ, Myriam Witvrouw, Zeger Debyser
Pages: 3615 - 3618 - Synthesis and biological evaluation of (11)C-labeled beta-galactosyl triazoles as potential PET tracers for in vivo LacZ reporter gene imaging(2009)
Authors: Sofie Celen, Christophe Deroose, Abdelilah Ibrahimi, Rik Gijsbers, Zeger Debyser, Luc Mortelmans, Alfons Verbruggen, Guy Bormans
Pages: 5117 - 5125 - Seeing genes at work in the living brain with non-invasive molecular imaging(2009)
Authors: Christophe Deroose, Veerle Reumers, Zeger Debyser, Veerle Baekelandt
Pages: 212 - 238 - Lens epithelium-derived growth factor/p75 interacts with the transposase-derived DDE domain of PogZ(2009)
Authors: Frauke Christ, Jelle Hendrix, Zeger Debyser, Rik Gijsbers, Jan De Rijck
Pages: 11467 - 11477
Patents
1 - 9 of 9
- Functional cure of retroviral infection (Inventor)
- Functional cure of retroviral infection (Inventor)
- Thieno[2,3-b]pyridine derivatives as viral replication inhibitors (Inventor)
- Functional cure of retroviral infection (Inventor)
- Thieno [2, 3-B] pyridine derivatives as viral replication inhibitors (Inventor)
- ;Antiviral compounds (Inventor)
- THIENO [2, 3-B] PYRIDINE DERIVATIVES AS VIRAL REPLICATION INHIBITORS (Inventor)
- VIRAL REPLICATION INHIBITORS (Inventor)
- NOVEL ANTIVIRAL COMPOUNDS (Inventor)