Researcher
Yves Briers
- Keywords:enzyme engineering, biomass degradation, Bacteriophages, Protein engineering, Synthetic biology, antibiotics
- Disciplines:Other biotechnology, bio-engineering and biosystem engineering not elsewhere classified, Industrial molecular engineering of nucleic acids and proteins, Medical biotechnology not elsewhere classified, Industrial microbiology, Biocatalysis and enzyme technology, Industrial biotechnology not elsewhere classified, Drug discovery and development not elsewhere classified, Synthetic biology, Infectious diseases, Molecular evolution, Microbiology not elsewhere classified, Virology
Affiliations
- Department of Biotechnology (Department)
Member
From1 Jan 2018 → Today - Department of Applied biosciences (Department)
Member
From1 Feb 2015 → 31 Dec 2017
Projects
1 - 10 of 36
- Function, organization, dynamics and evolution of hyperbranched receptor-binding protein systems in Klebsiella jumbo phages and their interactions with bacteriaFrom1 Jan 2024 → TodayFunding: FWO research project (including WEAVE projects)
- Engineered phages and tailocins targeting Shiga toxin-producing Escherichia coli (STEC)From1 Nov 2023 → 29 Feb 2024Funding: BOF - doctoral mandates
- Horizontal and vertical evolution of receptor-binding proteins in mono- and bivalent Klebsiella bacteriophagesFrom1 Oct 2023 → TodayFunding: FWO senior postdoctoral fellowship
- Directed evolution of modular proteins driven by machine learning: the VersaTile Platform 2.0From1 Apr 2023 → 30 Apr 2023Funding: BOF - doctoral mandates
- A high-throughput electroporation system for rapid strain development for industrial biotechnology purposesFrom15 Dec 2022 → TodayFunding: BOF - scientific equipment program
- Engineered lysines as innovative antimicrobial strategy for the treatment of coliform mastitisFrom1 Nov 2022 → TodayFunding: FWO Strategic Basic Research Grant
- A pipeline for phage lysins targeting multidrug-resistant Staphylococcus pseudintermedius in canine pyoderma and bacterial otitis externaFrom15 Oct 2022 → TodayFunding: IOF - technology validation in lab
- Understanding the evolutionary dynamics of phage lysin configurations as a driver for new enzyme-based antibioticsFrom1 Oct 2022 → TodayFunding: BOF - postdoctoral mandates
- Cofunding core facility - HTS for SynBioFrom1 Jul 2022 → TodayFunding: BOF - research organisations
- A market-fit and scalable pipeline for VersaTile antibodiesFrom1 Feb 2022 → 30 Nov 2023Funding: IOF - technology validation in lab
Publications
1 - 10 of 95
- Endolysin NC5 improves early cloxacillin treatment in a mouse model of Streptococcus uberis mastitis(2024)
Authors: Niels Vander Elst, Julie Bellemans, Rob Lavigne, Yves Briers, Evelyne Meyer
- Phage tailspike modularity and horizontal gene transfer reveals specificity towards E. coli O-antigen serogroups(2023)
Authors: Célia Pas, Agnieszka Łątka, Lars Fieseler, Yves Briers
- Current challenges in designer cellulosome engineering(2023)
Authors: Babette Lamote, Maria João de Carvalho Maurício da Fonseca, Julie Vanderstraeten, Kenan Meert, Marte Elias, Yves Briers
Pages: 2755 - 2770 - Foundation of the Belgian Society for Viruses of Microbes and meeting report of its inaugural symposium(2023)
Authors: Agnieszka Łątka, Abram Aertsen, Dimitri Boeckaerts, Bob Blasdel, Pieter-Jan Ceyssens, Abel Garcia-Pino, Annika Gillis, Rob Lavigne, Gipsi Lima-Mendez, Jelle Matthijnssens, et al.
- Phages and engineered lysins as an effective tool to combat Gram-negative foodborne pathogens(2023)
Authors: Aleksandra Maria Kocot, Yves Briers, Magdalena Plotka
Pages: 2235 - 2266 - Development of engineered endolysins with in vitro intracellular activity against streptococcal bovine mastitis‐causing pathogens(2023)
Authors: Niels Vander Elst, Joni Bert, Herman Favoreel, Rob Lavigne, Evelyne Meyer, Yves Briers
Pages: 2367 - 2386 - Distinct mode of action of a highly stable, engineered phage lysin killing Gram-negative bacteria(2023)
Authors: Hans Gerstmans, Lisa Duyvejonck, Roberto Vazquez Fernandez, Ines Staes, Jimmy Borloo, Karim Abdelkader, Jeroen Leroy, Emma Cremelie, Diana Gutierrez Fernandez, Héctor Tamés-Caunedo, et al.
- What's in a name? An overview of the proliferating nomenclature in the field of phage lysins(2023)
Authors: Roberto Vazquez Fernandez, Yves Briers
- Breaking down walls : towards a functional-based metagenomic discovery platform for phage-derived lysins(2023)
Authors: Iris Pottie, Lisa Duyvejonck, Roberto Vazquez Fernandez, Yves Briers
Number of pages: 1 - CkP1 bacteriophage, a S16-like myovirus that recognizes Citrobacter koseri lipopolysaccharide through its long tail fibers(2023)
Authors: Hugo Oliveira, Silvio Santos, Diana P. Pires, Dimitri Boeckaerts, Graca Pinto, Rita Domingues, Jennifer Otero, Yves Briers, Rob Lavigne, Mathias Schmelcher, et al.
Pages: 3621 - 3636
Patents
1 - 2 of 2
- VersaTile Shuffling (Inventor)
- VersaTile Shuffling (Inventor)