Researcher
Wim Van Hul
- Research Expertise:Genetic analyses of obesity and comorbidities and skeletal dysplasias
- Keywords:SKELETAL DYSPLASIAS, OBESITY, PAGET DISEASE, GENETIC DISEASE, Biomedical sciences (incl. biochemistry)
- Disciplines:Endocrinology and metabolic diseases, Molecular and cell biology, Metabolic diseases, Genetics
- Research techniques:DNA-sequencing, Next generation sequencing, cloning, expression studies, cell cultures, animal models (mouse and zebrafish)
- Users of research expertise:teams with complementary expertise and interest
Affiliations
- Medical Genetics (MEDGEN) (Research group)
Member
From1 Oct 2022 → Today - Medical genetics of obesity and skeletal disorders (MGENOS) (Research group)
Responsible
From1 Oct 2003 → 30 Sep 2022
Projects
1 - 10 of 27
- Precision Medicine Technologies (PreMeT)From1 Jan 2021 → TodayFunding: IOF - mandates
- Unraveling the Role of Paraoxonase 1 and 3 in the Etiology and Progression of Obesity and Obesity-Associated Liver Disease.From1 Nov 2020 → TodayFunding: FWO fellowships
- GENOmics in MEDicine: From whole genome sequencing towards personalized medicine (GENOMED).From3 Jul 2019 → TodayFunding: BOF - Methusalem, Fund Recuperation Fiscal Exemption
- The role of the paraoxonase gene family in obesity and obesity-associated liver disease following exposure to environmental pollutants or medical intervention strategies.From1 Jan 2019 → 31 Dec 2022Funding: BOF - projects
- Functional evaluation of the role of LRP4 and NPR3 in the regulation of bone metabolism by regulating respectively bone mass and bone growth.From1 Oct 2017 → 30 Sep 2020Funding: FWO fellowships
- Paget's disease of bone: molecular genetic investigation of the NFkB signaling regulating genes CBL, CBLB, and NR4A1 and functional validation in vitro and in Danio rerio.From1 Jan 2017 → 31 Dec 2020Funding: FWO Strategic Basic Research Grant
- Gene identification and zebrafish disease modeling of inherited bone disordersFrom1 Jan 2017 → 31 Dec 2021Funding: FWO scientific research network
- Study on the role of LRP4 in the regulation of Wnt signaling and bone formation.From1 Jan 2015 → 31 Dec 2018Funding: FWO research project (including WEAVE projects)
- GENOMED - Genomics in Medicine.From1 Jan 2015 → 31 Dec 2019Funding: BOF - Other initiatives, Fund Recuperation Fiscal Exemption
- Systems biology for the functional validation of genetic determinants of skeletal diseases (SYBIL).From1 Oct 2013 → 30 Sep 2018Funding: Health
Publications
21 - 30 of 177
- Delineation of a new fibrillin-2-opathy with evidence for a role of FBN2 in the pathogenesis of carpal tunnel syndrome(2021)
Authors: Silke Peeters, Arne Decramer, Stuart Alan Cain, Peter Houpt, Frederik Verstreken, Jan Noyez, Christophe Hermans, Werner Jacobs, Martin Lammens, Erik Fransen, et al.
Pages: 778 - 782 - A targeted multi-omics approach reveals paraoxonase-1 as a determinant of obesity-associated fatty liver disease(2021)
Authors: Sara Diels, Bart Cuypers, Asta Tvarijonaviciute, Bruno Derudas, Evelien Van Dijck, An Verrijken, Luc Van Gaal, Kris Laukens, Philippe Lefebvre, Jose J. Ceron, et al.
- Multiple bilateral hip fractures in a patient with dyskeratosis congenita caused by a novel mutation in the PARN gene(2021)
Authors: Z. Belaya, O. Golounina, A. Nikitin, N. Tarbaeva, E. Pigarova, E. Mamedova, M. Vorontsova, I. Shafieva, I. Demina, Wim Van Hul
Pages: 1227 - 1231 - Perspective of the GEMSTONE consortium on current and future approaches to functional validation for skeletal genetic disease using cellular, molecular and animal-modeling techniques(2021)
Authors: Martina Rauner, Ines Foessl, Melissa M. Formosa, Erika Kague, Vid Prijatelj, Nerea Alonso Lopez, Bodhisattwa Banerjee, Dylan Bergen, Bjoern Busse, Angelo Calado, et al.
- WNT16 Requires G alpha Subunits as Intracellular Partners for Both Its Canonical and Non-Canonical WNT Signalling Activity in Osteoblasts(2020)
Authors: Gretl Hendrickx, Eveline Boudin, Marinus Verbeek, Erik Fransen, Geert Mortier, Wim Van Hul
Pages: 294 - 302 - WNT signaling and bone(2020)
Authors: Yentl Huybrechts, Eveline Boudin, Wim Van Hul
- Spondylo-epi-metaphyseal dysplasia due to a homozygous missense mutation in the gene encoding Matrilin-3 (T120M)(2020)
Authors: Liza Das, Vandana Dhiman, Wim Van Hul, Anil Bhansali, Yashpal Gogate, Ellen Steenackers, Sanjay Kumar Bhadada
- DNA methylation profiling and genomic analysis in 20 children with short stature who were born small for gestational age(2020)
Authors: Ken Declerck, Muriel Thomas, Eveline Boudin, Dominique Beckers, Olimpia Chivu, Claudine Heinrichs, Koenraad Devriendt, Francis de Zegher, Wim Van Hul, Wim Vanden Berghe, et al.
- A multi-omics approach to elucidate risk factors for obesity and associated liver pathology(2020)
Authors: Sara Diels, Wim Van Hul, Wim Vanden Berghe
Number of pages: 238 - A multi-omics approach expands the mutational spectrum of MAP2K1-related melorheostosis(2020)
Authors: Raphaël De Ridder, Eveline Boudin, M. Carola Zillikens, Joe Ibrahim, Bram C. J. van der Eerden, Wim Van Hul
Pages: 1 - 8