Researcher
Vitor Bernardes Pinheiro
- Disciplines:Synthetic biology, Molecular evolution, Proteins, Infectious diseases
Affiliations
- Medicinal Chemistry (Rega Institute) (Division)
Member
From1 Sep 2018 → Today
Projects
1 - 10 of 23
- Harnessing the Power of DNA-Encoded Libraries to Identify and Expand Novel Hits to Develop Urgently Needed P. aeruginosa AntibioticsFrom3 Oct 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Development of diagnostic and therapeutic applications from synthetic genetic materials.From18 Sep 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- From experimental NMR data towards a software tool to predict optimal sequences for therapeutic morpholino oligonucleotidesFrom15 Jul 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Spatial control of enzymatic DNA assembly using ion charging layersFrom14 Jun 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Developing biological circuits for non-model organismsFrom23 Sep 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Directed evolution of bioactive compounds: Azol(in)e-containing post-translationally modified peptidesFrom5 Jul 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Redesigning Biology: Changing the substrate requirements of DNA polymerases by directed evolutionFrom20 Dec 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- COLUMBO: Engineered CRISPR toolbox for revolutionizing single-cell genome imaging in embryogenesis and oncologyFrom1 Oct 2021 → TodayFunding: BOF - projects
- Symmetric antibodies for symmetric epitopes: development and validation of the Symbody platform.From1 Oct 2021 → TodayFunding: IOF - technology validation in lab
- Synthetic Biology of mRNAFrom1 Mar 2021 → TodayFunding: H2020-EU.1.2.- EXCELLENT SCIENCE - Future and Emerging Technologies (FET)
Publications
11 - 20 of 24
- Engineering-driven biological insights into DNA polymerase mechanism(2019)
Authors: Vitor Bernardes Pinheiro
Pages: 9 - 16 - Rational design of an XNA ligase through docking of unbound nucleic acids to toroidal proteins(2019)
Authors: Michiel Vanmeert, Muhammad Usman Mirza, Stephen Weeks, Jef Rozenski, Mathy Froeyen, Piet Herdewyn, Vitor Bernardes Pinheiro, Eveline Lescrinier
Pages: 1 - 12 - E. coli surface display of streptavidin for directed evolution of an allylic deallylase (vol 9, pg 5383, 2018)(2019)
Authors: Tillmann Heinisch, Fabian Schwizer, Brett Garabedian, Eszter Csibra, Markus Jeschek, Jaicy Vallapurackal, Vitor Bernardes Pinheiro, Philippe Marliere, Sven Panke, Thomas R Ward
Pages: 6735 - 6735 - Construction and characterization of metal ion-containing DNA nanowires for synthetic biology and nanotechnology(2019)
Authors: Simon Vecchioni, Mark C Capece, Emily Toomey, Nguyen Le, Austin Ray, Alissa Greenberg, Kosuke Fujishima, Jesica Urbina, Ivan G Paulino-Lima, Vitor Bernardes Pinheiro, et al.
- Two New Plasmid Post-segregational Killing Mechanisms for the Implementation of Synthetic Gene Networks in Escherichia coli(2019)
Authors: Vitor Bernardes Pinheiro
Pages: 323 - + - Kinetic analysis of N-alkylaryl carboxamide hexitol nucleotides as substrates for evolved polymerases.(2019)
Authors: Marleen Renders, Shrinivas Dumbre, Mikhail Abramov, Donaat Kestemont, Vitor Bernardes Pinheiro, Piet Herdewyn
Pages: 2160 - 2168 - XNA Synthesis and Reverse Transcription by Engineered Thermophilic Polymerases.(2018)
Authors: Vitor Bernardes Pinheiro
Pages: e47 - Methylated Nucleobases: Synthesis and Evaluation for Base Pairing In Vitro and In Vivo(2018)
Authors: Amit Jabgunde, Mathy Froeyen, Mikhail Abramov, Eveline Lescrinier, Vitor Bernardes Pinheiro, Piet Herdewyn
Pages: 12695 - 12707 - XNA ligation using T4 DNA ligase in crowding conditions(2018)
Authors: Donaat Kestemont, Marleen Renders, Piotr Leonczak, Mikhail Abramov, Vitor Bernardes Pinheiro, Jef Rozenski, Piet Herdewyn
Pages: 6408 - 6411 - Phosphonomethyl Oligonucleotides as Backbone-Modified Artificial Genetic Polymers(2018)
Authors: Jef Rozenski, Shrinivas Dumbre, Vitor Bernardes Pinheiro, Elisabetta Groaz, Piet Herdewyn
Pages: 6690 - 6699