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Researcher
Veerle Janssens
- Disciplines:Proteins, Cell division, Cell signalling, Posttranslational modifications, Cancer biology, Cancer therapy, Developmental biology, Genetics
Affiliations
- Laboratory of Protein Phosphorylation and Proteomics (Division)
Responsible
From1 Oct 2021 → Today - Laboratory of Protein Phosphorylation and Proteomics (Division)
Member
From1 Oct 2007 → Today
Projects
1 - 10 of 23
- Next-generation, multi-technology immune-monitoring and easy-access spectral flow cytometryFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Integrated, multimodal phenotypic analysis of Ppp2r1a knockin mice: new in vivo models of syndromic PP2A-related (neuro)developmental disorders.From1 Oct 2021 → TodayFunding: FWO junior postdoctoral fellowship
- Insights into the disease mechanisms of PPP2R5D, PPP2R5C and PPP2R1A syndromes: towards therapeutic avenuesFrom1 Jul 2021 → TodayFunding: Foreign private sponsor - undefined
- Protein Phosphatase 2A dysfunctions in malignant pleural mesothelioma: oncogenic mechanisms and therapeutic opportunitiesFrom22 Mar 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Protein Phosphatase 2A dysfunctions in malignant pleural mesothelioma: oncogenic mechanisms and therapeutic opportunitiesFrom1 Mar 2021 → TodayFunding: Foundations, funds and other with scientific goal
- PPP2R1A as a new biomarker in type-II endometrial cancers.From1 Jan 2021 → TodayFunding: Foundations, funds and other with scientific goal
- PPP2R5D-related neurodevelopmental disorders: pathologic mechanisms and therapeutic avenuesFrom14 Sep 2020 → 15 Feb 2023Funding: Foundations, funds and other with scientific goal
- Function of PP2A methylesterase-1 PME-1 in the stress response: implications for glioblastoma treatmentFrom1 Jan 2019 → 15 Dec 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Function and post-translational regulation of the PP2A methylesterase PME-1 in the cellular response to stress conditionsFrom1 Jan 2019 → 31 Dec 2022Funding: FWO research project (including WEAVE projects)
- 3-year-research proposal, submitted 1 Nov 2018 to JORDAN'S GUARDIAN ANGELS FOUNDATION-by prof.dr. Veerle Janssens (KU Leuven, Leuven, Belgium)From1 Jul 2018 → 30 Jun 2021Funding: Foreign private sponsor - undefined
Publications
31 - 40 of 83
- Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 Axis(2019)
Authors: Veerle Janssens
Pages: 798 - + - De Novo Mutations Affecting the Catalytic C alpha Subunit of PP2A, PPP2CA, Cause Syndromic Intellectual Disability Resembling Other PP2A-Related Neurodevelopmental Disorders (vol 104, pg 139, 2019)(2019)
Authors: Saar Reynhout, Sandra Jansen, Dorien Haesen, Siska van Belle, Sonja A de Munnik, Ernie MHF Bongers, Jolanda H Schieving, Carlo Marcelis, Jeanne Amiel, Marlene Rio, et al.
Pages: 357 - 357 - De Novo Mutations Affecting the Catalytic Cα Subunit of PP2A (PPP2CA) Cause Syndromic Intellectual Disability Resembling Other PP2A-Related Neurodevelopmental Disorders.(2019)
Authors: Saar Reynhout, Siska Van Belle, Veerle Janssens
Pages: 139 - 156 - Protein Phosphatases as Critical Regulators for Cellular Homeostasis(2019)
Authors: Veerle Janssens
Pages: 1 - 1 - Physiologic functions of PP2A: Lessons from genetically modified mice(2019)
Authors: Saar Reynhout, Veerle Janssens
Pages: 31 - 50 - Identification of PP2A/Set binding sites and design of interacting peptides with potential clinical applications(2018)
Authors: Dorien Haesen, Etienne Waelkens, Veerle Janssens
Pages: 479 - 488 - Recurrent PPP2R1A mutations in type-II endometrial cancers: oncogenic mechanisms and therapeutic options(2018)
Authors: Michiel Remmerie, Dorien Haesen, Michael Ohlmeyer, Veerle Janssens
Pages: 165 - 166 - Targeted Therapies in Type II Endometrial Cancers: Too Little, but Not Too Late.(2018)
Authors: Michiel Remmerie, Veerle Janssens
- Protein kinase D displays intrinsic Tyr autophosphorylation activity: insights into mechanism and regulation(2018)
Authors: Rita Derua, Etienne Waelkens, Veerle Janssens, Johan Van Lint
Pages: 2432 - 2443 - Dephosphorylation of the HIV-1 restriction factor SAMHD1 is mediated by PP2A-B55α holoenzymes during mitotic exit(2018)
Authors: Rita Derua, Veerle Janssens
Patents
1 - 2 of 2
- Pro-apoptotic set and pp2a peptides (Inventor)
- Pro-apoptotic set and pp2a peptides (Inventor)