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Researcher
Veerle Janssens
- Disciplines:Proteins, Cell division, Cell signalling, Posttranslational modifications, Cancer biology, Cancer therapy, Developmental biology, Genetics
Affiliations
- Laboratory of Protein Phosphorylation and Proteomics (Division)
Responsible
From1 Oct 2021 → Today - Laboratory of Protein Phosphorylation and Proteomics (Division)
Member
From1 Oct 2007 → Today
Projects
1 - 10 of 23
- Next-generation, multi-technology immune-monitoring and easy-access spectral flow cytometryFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Integrated, multimodal phenotypic analysis of Ppp2r1a knockin mice: new in vivo models of syndromic PP2A-related (neuro)developmental disorders.From1 Oct 2021 → TodayFunding: FWO junior postdoctoral fellowship
- Insights into the disease mechanisms of PPP2R5D, PPP2R5C and PPP2R1A syndromes: towards therapeutic avenuesFrom1 Jul 2021 → TodayFunding: Foreign private sponsor - undefined
- Protein Phosphatase 2A dysfunctions in malignant pleural mesothelioma: oncogenic mechanisms and therapeutic opportunitiesFrom22 Mar 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Protein Phosphatase 2A dysfunctions in malignant pleural mesothelioma: oncogenic mechanisms and therapeutic opportunitiesFrom1 Mar 2021 → TodayFunding: Foundations, funds and other with scientific goal
- PPP2R1A as a new biomarker in type-II endometrial cancers.From1 Jan 2021 → TodayFunding: Foundations, funds and other with scientific goal
- PPP2R5D-related neurodevelopmental disorders: pathologic mechanisms and therapeutic avenuesFrom14 Sep 2020 → 15 Feb 2023Funding: Foundations, funds and other with scientific goal
- Function of PP2A methylesterase-1 PME-1 in the stress response: implications for glioblastoma treatmentFrom1 Jan 2019 → 15 Dec 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Function and post-translational regulation of the PP2A methylesterase PME-1 in the cellular response to stress conditionsFrom1 Jan 2019 → 31 Dec 2022Funding: FWO research project (including WEAVE projects)
- 3-year-research proposal, submitted 1 Nov 2018 to JORDAN'S GUARDIAN ANGELS FOUNDATION-by prof.dr. Veerle Janssens (KU Leuven, Leuven, Belgium)From1 Jul 2018 → 30 Jun 2021Funding: Foreign private sponsor - undefined
Publications
21 - 30 of 83
- Protein Phosphatase 2A (PP2A) mutations in brain function, development, and neurologic disease(2021)
Authors: Iris Verbinnen, Pieter Vaneynde, Rita Derua, Veerle Janssens
Pages: 1 - 22 - Deciphering the pathology of PP2A-related intellectual disability(2021)
Authors: Saar Reynhout, Veerle Janssens
- Zinc deficiency leads to reduced interleukin-2 production by active gene silencing due to enhanced CREMα expression in T cells(2021)
Authors: Veerle Janssens
- The broad phenotypic spectrum of PPP2R1A-related neurodevelopmental disorders correlates with the degree of biochemical dysfunction(2021)
Authors: Saar Reynhout, Iris Verbinnen, Koenraad Devriendt, Veerle Janssens
- Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis(2021)
Authors: Bob Meeusen, Veerle Janssens
Pages: 448 - + - Serine/Threonine Protein Phosphatases(2020)
Authors: Veerle Janssens
Number of pages: 16 - Differential proteomic analysis of hepatocellular carcinomas from Ppp2r5d knockout mice and normal (knockout) livers(2020)
Authors: Judit Domènech Omella, Louis Libbrecht, Rita Derua, Chantal Mathieu, Lut Overbergh, Etienne Waelkens, Veerle Janssens
Pages: 669 - 685 - An okadaic acid fragment analogue prevents nicotine-induced resistance to cisplatin by recovering PP2A activity in non-small cell lung cancer cells(2020)
Authors: Judit Domènech Omella, Veerle Janssens
- An okadaic acid fragment analogue prevents nicotine-induced resistance to cisplatin by recovering PP2A activity in non-small cell lung cancer cells(2020)
Authors: Judit Domènech Omella, Veerle Janssens
- PP2A: A Promising Biomarker and Therapeutic Target in Endometrial Cancer(2019)
Authors: Michiel Remmerie, Veerle Janssens
Patents
1 - 2 of 2
- Pro-apoptotic set and pp2a peptides (Inventor)
- Pro-apoptotic set and pp2a peptides (Inventor)