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Researcher
Veerle Janssens
- Disciplines:Proteins, Cell division, Cell signalling, Posttranslational modifications, Cancer biology, Cancer therapy, Developmental biology, Genetics
Affiliations
- Laboratory of Protein Phosphorylation and Proteomics (Division)
Responsible
From1 Oct 2021 → Today - Laboratory of Protein Phosphorylation and Proteomics (Division)
Member
From1 Oct 2007 → Today
Projects
1 - 10 of 23
- Next-generation, multi-technology immune-monitoring and easy-access spectral flow cytometryFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Integrated, multimodal phenotypic analysis of Ppp2r1a knockin mice: new in vivo models of syndromic PP2A-related (neuro)developmental disorders.From1 Oct 2021 → TodayFunding: FWO junior postdoctoral fellowship
- Insights into the disease mechanisms of PPP2R5D, PPP2R5C and PPP2R1A syndromes: towards therapeutic avenuesFrom1 Jul 2021 → TodayFunding: Foreign private sponsor - undefined
- Protein Phosphatase 2A dysfunctions in malignant pleural mesothelioma: oncogenic mechanisms and therapeutic opportunitiesFrom22 Mar 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Protein Phosphatase 2A dysfunctions in malignant pleural mesothelioma: oncogenic mechanisms and therapeutic opportunitiesFrom1 Mar 2021 → TodayFunding: Foundations, funds and other with scientific goal
- PPP2R1A as a new biomarker in type-II endometrial cancers.From1 Jan 2021 → TodayFunding: Foundations, funds and other with scientific goal
- PPP2R5D-related neurodevelopmental disorders: pathologic mechanisms and therapeutic avenuesFrom14 Sep 2020 → 15 Feb 2023Funding: Foundations, funds and other with scientific goal
- Function of PP2A methylesterase-1 PME-1 in the stress response: implications for glioblastoma treatmentFrom1 Jan 2019 → 15 Dec 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Function and post-translational regulation of the PP2A methylesterase PME-1 in the cellular response to stress conditionsFrom1 Jan 2019 → 31 Dec 2022Funding: FWO research project (including WEAVE projects)
- 3-year-research proposal, submitted 1 Nov 2018 to JORDAN'S GUARDIAN ANGELS FOUNDATION-by prof.dr. Veerle Janssens (KU Leuven, Leuven, Belgium)From1 Jul 2018 → 30 Jun 2021Funding: Foreign private sponsor - undefined
Publications
11 - 20 of 83
- Structural mechanism for inhibition of PP2A-B56α and oncogenicity by CIP2A(2023)
Authors: Judit Domènech Omella, Rita Derua, Veerle Janssens
- 2D-DIGE Analysis of Liver Disease in Mice(2023)
Authors: Rita Derua, Lut Overbergh, Veerle Janssens
Pages: 231 - 244 - LGR6 in Chronic Lung Diseases(2022)
Authors: Emanuela Elsa Cortesi, Tania Roskams, Veerle Janssens
- The role of serine/threonine phosphatases in human development: Evidence from congenital disorders(2022)
Authors: Pieter Vaneynde, Iris Verbinnen, Veerle Janssens
- Clinical, neuroimaging and molecular characteristics of PPP2R5D-related neurodevelopmental disorders: an expanded series with functional characterisation and genotype-phenotype analysis.(2022)
Authors: Pieter Vaneynde, Rita Derua, Veerle Janssens
- Clinical and molecular characteristics of a novel rare de novo variant in PPP2CA in a patient with a developmental disorder, autism, and epilepsy.(2022)
Authors: Iris Verbinnen, Chris Ulens, Veerle Janssens
- Increased LGR6 expression sustains long-term Wnt activation and acquisition of senescence in epithelial progenitors in chronic lung diseases(2021)
Authors: Emanuela Elsa Cortesi, Arno Vanstapel, Stijn Verleden, Bart Vanaudenaerde, Wim Wuyts, Wim Janssens, Veerle Janssens, Tania Roskams
- De rol van de Proteïne Fosfatase 2A Activator PTPA in KRAS-mutante niet-kleincellige longkankerontwikkeling en behandelingsresistentie(2021)
Authors: Bob Meeusen, Veerle Janssens, Johan Van Lint, Rita Derua
- PPP2R4 dysfunction promotes KRAS-mutant lung adenocarcinoma development and mediates opposite responses to MEK and mTOR inhibition(2021)
Authors: Bob Meeusen, Emanuela Elsa Cortesi, Judit Domènech Omella, Anna Sablina, Juan-Jose Ventura, Veerle Janssens
Pages: 57 - 67 - Serine/Threonine Protein Phosphatases(2021)
Authors: Veerle Janssens
Pages: 384 - 397
Patents
1 - 2 of 2
- Pro-apoptotic set and pp2a peptides (Inventor)
- Pro-apoptotic set and pp2a peptides (Inventor)