Researcher
Toon Laeremans
- Keywords:Biology, Applied biological sciences, biotechnology
- Disciplines:Other biological sciences not elsewhere classified
Affiliations
- Department of Bio-engineering Sciences (Department)
Member
From8 Apr 2019 → Today - Department of Bio-engineering Sciences (Department)
Member
From15 May 2010 → 20 Oct 2022 - Structural Biology Brussels (Research group)
Member
From15 May 2010 → 30 Sep 2020 - Biology (Department)
Member
From1 Jan 1999 → 28 Feb 2002
Publications
1 - 10 of 15
- A topological switch in CFTR modulates channel activity and sensitivity to unfolding(2021)
Authors: Daniel Scholl, Maud Sigoillot, Marie Overtus, Rafael Colomer Martinez, Chloé Martens, Yiting Wang, Els Pardon, Toon Laeremans, Abel Garcia-Pino, Jan Steyaert, et al.
Pages: 989-997 - Development of Generic G Protein Peptidomimetics Able to Stabilize Active State G(s) Protein-Coupled Receptors for Application in Drug Discovery(2021)
Authors: M Mannes, Charlotte Martin, Sarah Triest, Marilisa Pia Dimmito, Adriano Mollica, Toon Laeremans, Christel Menet, Steven Ballet
Pages: 10247-10254 - Domain-interface dynamics of CFTR revealed by stabilizing nanobodies(2019)
Authors: Maud Sigoillot, Marie Overtus, Magdalena Grodecka, Daniel Scholl, Abel Garcia-Pino, Toon Laeremans, Lihua He, Els Pardon, Ellen Hildebrandt, Ina L. Urbatsch, et al.
- A Genetically Encoded Biosensor Reveals Location Bias of Opioid Drug Action(2018)
Authors: Miriam Stoeber, Damien Jullié, Braden T Lobingier, Toon Laeremans, Jan Steyaert, Peter W. Schiller, Aashish Manglik, Mark Von Zastrow
Pages: 963-976.e5 - Nanobody-Enabled Reverse Pharmacology on G-Protein-Coupled Receptors. IF 12.257(2018)
Authors: Els Pardon, Cecilia Betti, Toon Laeremans, Florent Chevillard, Karel Jules Guillemyn, Peter Kolb, Steven Ballet, Jan Steyaert
Pages: 5292-5295 - Development by Genetic Immunization of Monovalent Antibodies Against Human Vasoactive Intestinal Peptide Receptor 1 (VPAC1), New Innovative, and Versatile Tools to Study VPAC1 Receptor Function(2018)
Authors: Xavier Peyrassol, Toon Laeremans, Vannessa Lahura, Maja Debulpaep, Hassan El Hassan, Jan Steyaert, Marc Parmentier, Ingrid Langer
- DNA immunization combined with scFv phage display identifies antagonistic GCGR specific antibodies and reveals new epitopes on the small extracellular loops(2016)
Authors: Bas van der Woning, Gitte De Boeck, Christophe Blanchetot, Vladimir Bobkov, Alex Klarenbeek, Michael Saunders, Magali Waelbroeck, Toon Laeremans, Jan Steyaert, Anna Hultberg, et al.
Pages: 1126-1135 - Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies(2016)
Authors: Dominique Burger, Martine Stihle, Ashwani Sharma, Paola Di Lello, Jörg Benz, Brigitte D'Arcy, Maja Debulpaep, David Fry, Walter Huber, Thomas Kremer, et al.
Pages: 16292-16306 - Development by Genetic Immunization of Monovalent Antibodies (Nanobodies) Behaving as Antagonists of the Human ChemR23 Receptor(2016)
Authors: Xavier Peyrassol, Toon Laeremans, Mieke Gouwy, Vannessa Lahura, Maja Debulpaep, Jo Van Damme, Jan Steyaert, Marc Parmentier, Ingrid Langer
Pages: 2893-2901 - Modular integrated secretory system engineering in Pichia pastoris to enhance G-protein coupled receptor expression(2016)
Authors: Katrien Claes, Kristof Vandewalle, Bram Laukens, Toon Laeremans, Olivier Vosters, Ingrid Langer, Marc Parmentier, Jan Steyaert, Nico Callewaert
Pages: 1070-1075
Patents
1 - 10 of 10
- Cystic fibrosis transmembrane conductance regulator stabilizing agents
- Binding domains directed against gpcr: g protein complexes and uses derived thereof
- Protein binding domains stabilizing functional conformational states of gpcrs and uses thereof (Inventor)
- Protein binding domains stabilizing functional conformational states of gpcrs and uses thereof (Inventor)
- Protein binding domains stabilizing functional conformational states of gpcrs and uses thereof
- Protein binding domains stabilizing functional conformational states of gpcrs and uses thereof
- Opioid receptor binding agents and uses thereof
- Tools and methods for expression of membrane proteins
- Protein binding domains stabilizing functional conformational states of gpcrs and uses thereof
- Cystic fibrosis transmembrane conductance regulator stabilizing agents (Inventor)