Researcher
Tom Taghon
- Disciplines:Developmental biology, Hematology not elsewhere classified, Immunology not elsewhere classified
Affiliations
- Department of Diagnostic Sciences (Department)
Member
From1 Oct 2018 → Today - Dean's Office of the Faculty of Medicine and Health Sciences (Administrative office)
Member
From1 Jul 2002 → 31 Oct 2002 - Department of Clinical chemistry, microbiology and immunology (Department)
Member
From1 Jan 1998 → 30 Sep 2018
Projects
1 - 10 of 48
- Clinical Tissue and Cell Culture coreFrom1 Feb 2024 → TodayFunding: BOF - research organisations
- Single-cell SPACE, the next frontierFrom1 Jan 2024 → TodayFunding: BOF - projects
- Automated production and expansion of cell therapy productsFrom20 Dec 2023 → TodayFunding: IOF - technology validation in lab
- Engineering of universal iPSC-derived therapeutic cells by nanofiber photoporation.From1 Nov 2023 → TodayFunding: FWO Strategic Basic Research Grant
- Engineering of universal iPSC-derived therapeutic cells by nanofiber photoporation.From1 Oct 2023 → 31 Oct 2023Funding: BOF - doctoral mandates
- Special Research Fund Professorship in immunologyFrom1 Sep 2023 → TodayFunding: BOF - ZAP BOF mandates
- Deregulated mRNA transcription and protein translation in the transformation of normal T-cells to malignant cells.From1 Jan 2023 → TodayFunding: BOF - iBOF
- Cofunding core facility - Flow cytometryFrom1 Nov 2022 → TodayFunding: BOF - research organisations
- NOn-VIral gene modified STEM cell therapyFrom1 Nov 2022 → TodayFunding: HORIZON.3.1 - European Innovation Council (EIC)
- Unraveling the Role of GATA3 in B-Cell Precursor Acute Lymphoblastic LeukemiaFrom1 Nov 2022 → TodayFunding: BOF - postdoctoral mandates
Publications
31 - 40 of 137
- Posttranslational regulation of the exon skipping machinery controls aberrant splicing in leukemia(2020)
Authors: Yalu Zhou, Cuijuan Han, Eric Wang, Adam H. Lorch, Valentina Serafin, Byoung-Kyu Cho, Blanca T. Guttierrez Diaz, Julien Calvo, Celestia Fang, Alireza Khodadadi-Jamayran, et al.
Pages: 1388 - 1409 - Distinct and temporary-restricted epigenetic mechanisms regulate human αβ and γδ T cell development(2020)
Authors: Anna Kuchmiy, Matthias De Decker, Steven Strubbe, Marieke Lavaert, Georges Leclercq, Filip Van Nieuwerburgh, Pieter Van Vlierberghe, Tom Taghon
Pages: 1280 - 1292 - Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma(2020)
Authors: Renate De Smedt, Julie Morscio, Lindy Reunes, Juliette Roels, Valentina Bardelli, Béatrice Lintermans, Wouter Van Loocke, Afonso Almeida, Laurence C. Cheung, Rishi S. Kotecha, et al.
Pages: 1685 - 1695 - hsa-miR-20b-5p and hsa-miR-363-3p affect expression of PTEN and BIM tumor suppressor genes and modulate survival of T-ALL cells in vitro(2020)
Authors: Monika Drobna, Bronislawa Szarzynska, Roman Jaksik, Lukasz Sedek, Anna Kuchmiy, Tom Taghon, Pieter Van Vlierberghe, Tomasz Szczepanski, Michal Witt, Malgorzata Dawidowska
- The transcription factor ETS1 is an important regulator of human NK cell development and terminal differentiation(2020)
Authors: Sylvie Taveirne, Sigrid Wahlen, Wouter Van Loocke, Els Van Ammel, Katrien De Mulder, Laurentijn Tilleman, Marc Aumercier, Patrick Matthys, Filip Van Nieuwerburgh, Tom Taghon, et al.
Pages: 288 - 298 - Human thymic CD10+ PD-1+ intraepithelial lymphocyte precursors acquire interleukin-15 responsiveness at the CD1a– CD95+ CD28– CCR7– developmental stage(2020)
Authors: Lore Billiet, Glenn Goetgeluk, Sarah Bonte, Stijn De Munter, Laurenz De Cock, Melissa Pille, Joline Ingels, Hanne Jansen, Karin Weening, Filip Van Nieuwerburgh, et al.
- T-cells with a single tumor antigen-specific T-cell receptor can be generated in vitro from clinically relevant stem cell sources(2020)
Authors: Sarah Bonte, Stijn De Munter, Glenn Goetgeluk, Joline Ingels, Melissa Pille, Lore Billiet, Tom Taghon, Georges Leclercq, Bart Vandekerckhove, Tessa Kerre
- Distinct Notch1 and BCL11B requirements mediate human γδ/αβ T cell development(2020)
Authors: Anne-Catherine Dolens, Kaat Durinck, Marieke Lavaert, Joni Van der Meulen, Imke Velghe, Jelle De Medts, Karin Weening, Juliette Roels, Katrien De Mulder, Pieter-Jan Volders, et al.
- PHF6 expression levels impact human hematopoietic stem cell differentiation(2020)
Authors: Anne-Catherine Dolens, Steven Strubbe, Inge Van de Walle, Finola E. Moore, Suzanne Vanhauwaert, Filip Matthijssens, David M. Langenau, Pieter Van Vlierberghe, Tom Taghon
- Integrated scRNA-seq identifies human postnatal thymus seeding progenitors and regulatory dynamics of differentiating immature thymocytes(2020)
Authors: Marieke Lavaert, Niels Vandamme, Jong-Eun Park, Monica S. Kowalczyk, Bo Li, Orr Ashenberg, Marcin Tabaka, Danielle Dionne, Timothy L. Tickle, Michal Slyper, et al.
Pages: 1088 - 1104.e6