Researcher
Tom Taghon
- Disciplines:Developmental biology, Hematology not elsewhere classified, Immunology not elsewhere classified
Affiliations
- Department of Diagnostic Sciences (Department)
Member
From1 Oct 2018 → Today - Dean's Office of the Faculty of Medicine and Health Sciences (Administrative office)
Member
From1 Jul 2002 → 31 Oct 2002 - Department of Clinical chemistry, microbiology and immunology (Department)
Member
From1 Jan 1998 → 30 Sep 2018
Projects
1 - 10 of 48
- Clinical Tissue and Cell Culture coreFrom1 Feb 2024 → TodayFunding: BOF - research organisations
- Single-cell SPACE, the next frontierFrom1 Jan 2024 → TodayFunding: BOF - projects
- Automated production and expansion of cell therapy productsFrom20 Dec 2023 → TodayFunding: IOF - technology validation in lab
- Engineering of universal iPSC-derived therapeutic cells by nanofiber photoporation.From1 Nov 2023 → TodayFunding: FWO Strategic Basic Research Grant
- Engineering of universal iPSC-derived therapeutic cells by nanofiber photoporation.From1 Oct 2023 → 31 Oct 2023Funding: BOF - doctoral mandates
- Special Research Fund Professorship in immunologyFrom1 Sep 2023 → TodayFunding: BOF - ZAP BOF mandates
- Deregulated mRNA transcription and protein translation in the transformation of normal T-cells to malignant cells.From1 Jan 2023 → TodayFunding: BOF - iBOF
- Cofunding core facility - Flow cytometryFrom1 Nov 2022 → TodayFunding: BOF - research organisations
- NOn-VIral gene modified STEM cell therapyFrom1 Nov 2022 → TodayFunding: HORIZON.3.1 - European Innovation Council (EIC)
- Unraveling the Role of GATA3 in B-Cell Precursor Acute Lymphoblastic LeukemiaFrom1 Nov 2022 → TodayFunding: BOF - postdoctoral mandates
Publications
121 - 130 of 137
- T-lymphoid differentiation potential measured in vitro is higher in CD34+CD38-/lo hematopoietic stem cells from umbilical cord blood than from bone marrow and is an intrinsic property of the cells(2011)
Authors: Magda De Smedt, Georges Leclercq, Tom Taghon, Jean Plum
Pages: 646 - 654 - Regulatory networks governed by microRNAs in T-ALL oncogenesis and normal T-cell development(2011)Volume: 118
Authors: Joni Van der Meulen, Evelien Mets, Pieter Mestdagh, Peter Pipelers, Tom Taghon, David Camacho Trujillo, David Avran, Gert Van Peer, Nadine Van Roy, Olivier Thas, et al.
Pages: 599 - 599 - PHF6 mutations in T-cell acute lymphoblastic leukemia(2010)
Authors: Pieter Van Vlierberghe, Teresa Palomero, Hossein Khiabanian, Joni Van der Meulen, Mireia Castillo, Jan Philippé, Sara Gonzalez-Garcia, Maria L Toribio, Tom Taghon, Linda Zuurbier, et al.
Pages: 338 - U95 - Continuous CD27 triggering in vivo strongly reduces NK cell numbers(2010)
Authors: Veerle De Colvenaer, Sylvie Taveirne, Jörg Hamann, Alex M de Bruin, Magda De Smedt, Tom Taghon, Jean Plum, René van Lier, Georges Leclercq
Pages: 1107 - 1117 - Notch signaling is required for proliferation but not for differentiation at a well-defined β-selection checkpoint during human T-cell development(2009)
Authors: Tom Taghon, Inge Van de Walle, Greet De Smet, Magda De Smedt, Georges Leclercq, Jean Plum
Pages: 3254 - 3263 - MICRORNA SIGNATURES IN GENETIC SUBTYPES OF T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA(2009)Volume: 94
Authors: Joni Van der Meulen, Pieter Van Vlierberghe, Pieter Mestdagh, Jo Vandesompele, Bruce Poppe, Nadine Van Roy, Tom Taghon, Jean Plum, B. Cauwelier, DLD Selleslag, et al.
Pages: 427 - 427 - An early decrease in Notch activation is required for human TCR-αβ lineage differentiation at the expense of TCR-γδ T cells(2009)
Authors: Inge Van de Walle, Greet De Smet, Magda De Smedt, Georges Leclercq, Jean Plum, Tom Taghon
Pages: 2988 - 2998 - CD4 and CD8 TCR alpha beta cells are selected on MHC expressed on thymocyte precursors in OP9-DL1 cultures(2009)Volume: 114
Authors: Stefanie Van Coppernolle, Bart Vandekerckhove, Greet Verstichel, Imke Velghe, Tom Taghon, Georges Leclercq, Jean Plum, Tessa Kerre
Pages: 1414 - 1414 - Functionally mature CD4 and CD8 TCRαβ cells are generated in OP9-DL1 cultures from human CD34+ hematopoietic cells(2009)
Authors: Stefanie Van Coppernolle, Greet Verstichel, Frank Timmermans, Imke Velghe, David Vermijlen, Magda De Smedt, Georges Leclercq, Jean Plum, Tom Taghon
Pages: 4859 - 4870 - Regulation of early T cell development in mouse and human by Notch(2009)
Authors: Tom Taghon
Pages: 301 - 314