Researcher
Tom Taghon
- Disciplines:Developmental biology, Hematology not elsewhere classified, Immunology not elsewhere classified
Affiliations
- Department of Diagnostic Sciences (Department)
Member
From1 Oct 2018 → Today - Dean's Office of the Faculty of Medicine and Health Sciences (Administrative office)
Member
From1 Jul 2002 → 31 Oct 2002 - Department of Clinical chemistry, microbiology and immunology (Department)
Member
From1 Jan 1998 → 30 Sep 2018
Projects
1 - 10 of 35
- Deregulated mRNA transcription and protein translation in the transformation of normal T-cells to malignant cells.From1 Jan 2023 → TodayFunding: BOF - iBOF
- Cofunding core facility - Flow cytometryFrom1 Nov 2022 → TodayFunding: BOF - research organisations
- Unraveling the Role of GATA3 in B-Cell Precursor Acute Lymphoblastic LeukemiaFrom1 Nov 2022 → TodayFunding: BOF - postdoctoral mandates
- Identification of the molecular drivers of ab vs. gd T cell development at single cell resolution in humanFrom1 Oct 2022 → TodayFunding: FWO junior postdoctoral fellowship
- SpatialConnect: linking tissue biology to the new era of single-cell spatial transcriptomicsFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- The generation of bona fide T cell precursors for cell therapyFrom15 Apr 2022 → TodayFunding: IOF - technology validation in lab
- Functional analysis of the RNA helicase DHX15 in T-cell acutelymphoblastic leukemiaFrom1 Jan 2022 → TodayFunding: FWO research project
- Origin and molecular drivers of T cell and dendritic cell development in the human thymus.From1 Oct 2021 → TodayFunding: BOF - projects
- Deciphering the functional phenotype of U+03B3U+03B4 T cells in spondyloarthritis.From1 Oct 2021 → 31 Oct 2021Funding: BOF - doctoral mandates
- Rapid ex-vivo detection, quantification and characterisation of cell-mediated immune responses induced by natural infection or vaccination with SARS-CoV-2 orr other pathogens.From1 Apr 2021 → 31 Mar 2023Funding: IOF - technology validation in lab
Publications
1 - 10 of 129
- Pre-clinical evaluation of the hypomethylating agent decitabine for the treatment of T-cell lymphoblastic lymphoma(2023)
Authors: Lien Provez, Tom Putteman, Mattias Landfors, Juliette Roels, Lindy Reunes, Sara T'Sas, Wouter Van Loocke, Béatrice Lintermans, Stien De Coninck, Morgan Thenoz, et al.
- Identification and purification of human T cell precursors(2022)Edition: 2Series: Methods in Molecular Biology (MIMB)
Authors: Inge Van de Walle, Nina Lambrechts, Anaïs Derveeuw, Marieke Lavaert, Juliette Roels, Tom Taghon
Pages: 315 - 333 - TXNIP promotes human NK cell development but is dispensable for NK cell functionality(2022)
Authors: Eva Persyn, Sigrid Wahlen, Laura Kiekens, Sylvie Taveirne, Wouter Van Loocke, Els Van Ammel, Filip Van Nieuwerburgh, Tom Taghon, Bart Vandekerckhove, Pieter Van Vlierberghe, et al.
- Development of gamma delta T cells in the thymus : a human perspective(2022)
Authors: Lena Böhme, Juliette Roels, Tom Taghon
- Multiomics to investigate the mechanisms contributing to repression of PTPRC and SOCS2 in pediatric T-ALL : focus on miR-363-3p and promoter methylation(2022)
Authors: Monika Drobna-Sledzinska, Natalia Mackowska-Maslak, Roman Jaksik, Maria Kosmalska, Bronislawa Szarzynska, Monika Lejman, Lukasz Sedek, Tomasz Szczepanski, Tom Taghon, Pieter Van Vlierberghe, et al.
Pages: 720 - 733 - Small-scale manufacturing of neoantigen-encoding messenger RNA for early-phase clinical trials(2022)
Authors: Joline Ingels, Laurenz De Cock, Rupert Mayer, Pam Devreker, Karin Weening, Nele Lootens, Saskia De Smet, Marieke Brusseel, Stijn De Munter, Melissa Pille, et al.
Pages: 213 - 222 - HES1 and HES4 have non-redundant roles downstream of Notch during early human T-cell development(2021)
Authors: Matthias De Decker, Marieke Lavaert, Juliette Roels, Laurentijn Tilleman, Bart Vandekerckhove, Georges Leclercq, Filip Van Nieuwerburgh, Pieter Van Vlierberghe, Tom Taghon
Pages: 130 - 141 - A DL-4-and TNF alpha-based culture system to generate high numbers of nonmodified or genetically modified immunotherapeutic human T-lymphoid progenitors(2021)
Authors: Ranjita Devi Moirangthem, Kuiying Ma, Sabrina Lizot, Anne Cordesse, Juliette Olivre, Corinne de Chappedelaine, Akshay Joshi, Agata Cieslak, John Tchen, Nicolas Cagnard, et al.
Pages: 1662 - 1676 - Treatment of a patient with severe cytomegalovirus (CMV) infection after haploidentical stem cell transplantation with donor-derived CMV-specific T cells(2021)
Authors: Joline Ingels, Saskia De Smet, Kelly Heyns, Nele Lootens, Jonas Segaert, Tom Taghon, Georges Leclercq, Karim Vermaelen, Evelyne Willems, Etienne Baudoux, et al.
Pages: 482 - 486 - PRL3 enhances T-cell acute lymphoblastic leukemia growth through suppressing T-cell signaling pathways and apoptosis(2021)
Authors: E. G. Garcia, A. Veloso, M. L. Oliveira, J. R. Allen, S. Loontiens, D. Brunson, D. Do, C. Yan, R. Morris, S. Iyer, et al.
Pages: 679 - 690