Researcher
Tom Desmet
- Keywords:biocatalysis, enzyme engineering, carbohydrate biotechnology
- Disciplines:Industrial molecular engineering of nucleic acids and proteins, Carbohydrates, Biocatalysis and enzyme technology
Affiliations
- Department of Biotechnology (Department)
Responsible
From1 Oct 2022 → Today - Department of Biotechnology (Department)
Member
From1 Oct 2022 → Today - Department of Biotechnology (Department)
Member
From1 Jan 2018 → Today - Department of Biochemical and microbial technology (Department)
Member
From1 Apr 2006 → 31 Dec 2017 - Department of Biochemistry and microbiology (Department)
Member
From1 Jan 2001 → 31 Mar 2006
Projects
1 - 10 of 32
- Oligosaccharide purification system – effective purification of short oligosaccharidesFrom20 Dec 2023 → TodayFunding: IOF - technology validation in lab
- The quest for an aldose C3-epimerase: the missing link in sugar conversionsFrom1 Nov 2023 → TodayFunding: FWO fellowships
- Guided by Nature: enzyme tunnel evolution as a tool for functional adaptationFrom1 Nov 2023 → TodayFunding: BOF - doctoral mandates
- Off the beaten path of protein evolution: insertions and deletions as drivers of functional innovationFrom1 Oct 2023 → TodayFunding: FWO senior postdoctoral fellowship
- Rational design and synthesis of non-hallucinogenic psilocin analogues as selective 5-HT2A receptor agonists with therapeutic potentialFrom1 Oct 2023 → TodayFunding: BOF - doctoral mandates
- Radical-based Enzymatic Degradation of Organic Pollutants (REDOP)From1 Nov 2022 → TodayFunding: FWO Strategic Basic Research Grant
- Cofunding core facility - HTS for SynBioFrom1 Jul 2022 → TodayFunding: BOF - research organisations
- MyCOS - Synthetic biology for a sustainable conversion of fungal chitin-rich waste streams into valuable biobased chitooligosaccharides for plant healthFrom1 Jan 2022 → 31 Dec 2023Funding: FWO Thematic call for research projects in the field of bioeconomy
- Evolution in practice: converting hydrolases and transferases into phosphorylasesFrom1 Nov 2021 → TodayFunding: FWO fellowships
- Unlocking the specificity determinants in nucleotide sugar epimerasesFrom1 Nov 2021 → TodayFunding: FWO fellowships
Publications
21 - 30 of 34
- CorNet : assigning function to networks of co-evolving residues by automated literature mining(2017)
Authors: Tom van den Bergh, Giorgio Tamo, Alberto Nobili, Yifeng Tao, Tianwei Tan, Uwe T Bornscheuer, Remko KP Kuipers, Bas Vroling, René M de Jong, Kalyanasundaram Subramanian, et al.
- Trehalose analogues: latest insights in properties and biocatalytic production(2015)
Authors: Maarten Walmagh, Tom Desmet
Pages: 13729 - 13745 - UDP-hexose 4-epimerases: a view on structure, mechanism and substrate specificity(2015)
Authors: Koen Beerens, Wim Soetaert, Tom Desmet
Pages: 8 - 14 - Characterization and mutational analysis of the UDP-Glc(NAc) 4-epimerase from Marinithermus hydrothermalis(2013)
Authors: Koen Beerens, Wim Soetaert, Tom Desmet
Pages: 7733 - 7740 - Enzymes for the biocatalytic production of rare sugars(2012)
Authors: Koen Beerens, Tom Desmet, Wim Soetaert
Pages: 823 - 834 - Broadening the synthetic potential of disaccharide phosphorylases through enzyme engineering(2012)
Authors: Tom Desmet, Wim Soetaert
Pages: 11 - 17 - Enzymatic glycosylation of small molecules: challenging substrates require tailored catalysts(2012)
Authors: Tom Desmet, Wim Soetaert, Pavla Bojarová, Vladimir Kren, Lubbert Dijkhuizen, Vanessa Eastwick-Field, Alexander Schiller
Pages: 10786 - 10801 - Enzymatic glycosyl transfer: mechanisms and applications(2011)
Authors: Tom Desmet, Wim Soetaert
Pages: 1 - 18 - Engineering of cellobiose phosphorylase for glycoside synthesis(2010)Volume: 150
Authors: Tom Desmet, Wim Soetaert
Pages: S85 - S85 - Crystallization and X-ray diffraction studies of cellobiose phosphorylase from Cellulomonas uda(2010)
Authors: Annelies Van Hoorebeke, Jan Stout, John Kyndt, Manu De Groeve, Ina Dix, Tom Desmet, Wim Soetaert, Jozef Van Beeumen, Savvas Savvides
Pages: 346 - 351
Patents
1 - 6 of 6
- Mutant sucrose phosphorylases with improved glycosylation activity towards polyphenols (Inventor)
- A sucrose phosphorylase for the production of kojibiose (Inventor)
- Mutant sucrose phosphorylases with improved glycosylation activity towards polyphenols (Inventor)
- A sucrose phosphorylase for the production of kojibiose (Inventor)
- Mutant sucrose synthases and their uses (Inventor)
- System for adaptive drug delivery (Inventor)