Researcher
Tim Lammens
- Keywords:acute myeloid leukemi, inherited predisposition for cancer, asparaginase, neuroblastoma, juvenile myelomonocytic leukemia, pediatric oncology
- Disciplines:Molecular and cell biology not elsewhere classified, Oncology not elsewhere classified, Genomics, Paediatrics
Affiliations
- Department of Internal Medicine and Pediatrics (Department)
Member
From1 Oct 2018 → Today - Department of Pediatrics and medical genetics (Department)
Member
From1 Jun 2009 → 30 Sep 2018 - Department of Plant Biotechnology and Bioinformatics (Department)
Member
From1 Oct 2004 → 31 Jan 2009
Projects
1 - 10 of 16
- Evaluating the predictive power of a set of adrenergic and mesenchymal coding - and - noncoding RNAs in neuroblastoma.From1 Mar 2024 → TodayFunding: Foreign foundations, funds with scientific view
- Facility : Patiënt-afgeleide xenograft modellen – UGent;From1 Feb 2024 → TodayFunding: BOF - research organisations
- Establishing safety and efficacy of an improved Asparaginase in dog models: final preparation for Phase I clinical trialFrom1 Jan 2024 → TodayFunding: Nonprofit institution or equivalents
- A SIOPEN pragmatic clinical trial to MOnitor NeuroblastomA relapse with LIquid biopsy Sensitive AnalysisFrom1 Jan 2024 → TodayFunding: HORIZON.2.1 - Health
- Towards clinical testing of novel stabilized less toxic asparaginases for the treatment of acute lymphoblastic leukemiaFrom20 Dec 2023 → TodayFunding: IOF - technology validation in lab
- Research assignment of Prof. dr. Tim Lammens, framing the ongoing clinical-translational research at the Department of Pediatric Hematology-Oncology and Stem Cell TransplantationFrom1 Oct 2023 → TodayFunding: Nonprofit institution or equivalents
- Preclinical validation of a less toxic variant for paediatric leukemiaFrom1 Oct 2022 → 30 Sep 2023Funding: Nonprofit institution or equivalents
- A patient derived xenograft (PDX) platform for in vivo evaluation of novel anticancer therapiesFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- The impact of magnetic particulate matter (mPM) pollution as a contributing factor for development of childhood cancer: an in vitro and in vivo molecular and cellular analysis.From1 Nov 2021 → 31 Oct 2022Funding: Nonprofit institution or equivalents
- The use of a less toxic alternative asparaginase variant to treat metastatic breast cancerFrom1 Oct 2021 → TodayFunding: BOF - projects
Publications
11 - 20 of 36
- Functional classification of RUNX1 variants in familial platelet disorder with associated myeloid malignancies(2021)
Authors: Melanie Decker, Tim Lammens, Alina Ferster, Miriam Erlacher, Ayami Yoshimi, Charlotte M. Niemeyer, Martijn P. T. Ernst, Marc H. G. P. Raaijmakers, Nicolas Duployez, Andreas Flaum, et al.
Pages: 3304 - 3308 - Favorable outcome of NUTM1-rearranged infant and pediatric B cell precursor acute lymphoblastic leukemia in a collaborative international study(2021)
Authors: Judith M. Boer, Maria Grazia Valsecchi, Femke M. Hormann, Zeljko Antic, Marketa Zaliova, Claire Schwab, Giovanni Cazzaniga, Chloé Arfeuille, Hélène Cavé, Andishe Attarbaschi, et al.
Pages: 2978 - 2982 - Germline SAMD9L triple-allelic mosaicism with independent segregation into biallelic offsprings : molecular support for non-mendelian inheritance(2021)Volume: 8
Authors: S Sahoo, C Goodings, M Angeles Lillo, Tim Lammens, J van der Werff ten Bosch, B Strahm, Barbara De Moerloose, M Wlodarski
Number of pages: 1 - Circulating non-coding RNAs in head and neck cancer : roles in diagnosis, prognosis, and therapy monitoring(2021)
Authors: Araceli Diez-Fraile, Joke De Ceulaer, Charlotte Derpoorter, Christophe Spaas, Tom De Backer, Philippe Lamoral, Johan Abeloos, Tim Lammens
- NUTM1-rearranged infant and pediatric B cell precursor acute lymphoblastic leukemia : a good prognostic subtype identified in a collaborative international study(2020)Volume: 136
Authors: Judith M. Boer, Maria Grazia Valsecchi, Femke M. Hormann, Zeljko Antic, Marketa Zaliova, Claire Schwab, Giovanni Cazzaniga, Chloe Arfeuille, Helene Cave, Andishe Attarbaschi, et al.
Number of pages: 1 - Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma(2020)
Authors: Renate De Smedt, Julie Morscio, Lindy Reunes, Juliette Roels, Valentina Bardelli, Béatrice Lintermans, Wouter Van Loocke, Afonso Almeida, Laurence C. Cheung, Rishi S. Kotecha, et al.
Pages: 1685 - 1695 - The altered transcriptome of pediatric myelodysplastic syndrome revealed by RNA sequencing(2020)
Authors: L Zubovic, S Piazza, T Tebaldi, L Cozzuto, G Palazzo, V Sidarovich, V De Sanctis, R Bertorelli, Tim Lammens, Mattias Hofmans, et al.
- Clinical significance of TARP expression in pediatric acute myeloid leukemia(2020)
Authors: Barbara Depreter, Barbara De Moerloose, Karl Vandepoele, Anne Uyttebroeck, An Van Damme, Barbara Denys, Laurence Dedeken, Marie-Françoise Dresse, Jutte Van Der Werff Ten Bosch, Mattias Hofmans, et al.
- Response-guided chemotherapy for pediatric acute myeloid leukemia without hematopoietic stem cell transplantation in first complete remission: Results from protocol DB AML-01(2019)
Authors: Barbara De Moerloose, Ardine Reedijk, Geertruida H. de Bock, Tim Lammens, Valerie de Haas, Barbara Denys, Laurence Dedeken, Marry M. van den Heuvel-Eibrink, Maroeska te Loo, Anne Uyttebroeck, et al.
- Pinpointing a potential role for CLEC12B in cancer predisposition through familial exome sequencing(2019)
Authors: Charlotte Derpoorter, Karl Vandepoele, Araceli Diez Fraile, Katrien Vandemeulebroecke, Bram De Wilde, Franki Speleman, Nadine Van Roy, Tim Lammens, Genevieve Laureys