Researcher
Thierry VandenDriessche
- Keywords (Vrije Universiteit Brussel):Medicine, Applied biological sciences, biotechnology
- Disciplines (Vrije Universiteit Brussel):Hematology, Neurological and neuromuscular diseases, Cancer therapy, Cardiology, Computational transcriptomics and epigenomics
- Disciplines (KU Leuven):Gene and molecular therapy
- See also: Thierry Vandendriessche (KU Leuven)
Affiliations
- Division of Gene Therapy & Regenerative Medicine (Research group)
Responsible
From19 Apr 2011 → Today - Basic (bio-) Medical Sciences (Department)
Member
From8 Apr 2019 → Today - Basic (bio-) Medical Sciences (Department)
Member
From1 Jan 2014 → 20 Oct 2022 - Cell Biology and Histology (Department)
Member
From1 Oct 2010 → 31 Dec 2013 - Department of Bio-engineering Sciences (Department)
Member
From1 Feb 2010 → 28 Feb 2010 - Immunology and Microbiology (Department)
Member
From1 Oct 2007 → 30 Sep 2010 - Department of Bio-engineering Sciences (Department)
Member
From1 Feb 2007 → 30 Sep 2010 - Department of Bio-engineering Sciences (Department)
Member
From1 Oct 2003 → 30 Sep 2004 - Centre for Molecular and Vascular Biology (Division)
Member
From1 Oct 1999 → Today - Department of General Biology (Research group)
Member
From1 Oct 1990 → 30 Sep 1994
Projects
1 - 10 of 17
- HERCULES: DEVELOPMENT OF NEXT-GENERATION GENE THERAPY TO TREAT GENETIC MUSCLE DISORDERSFrom1 Mar 2024 → TodayFunding: BOF - Methusalem
- HERCULES: Development of an innovative muscle-directed gene therapy platform for lysosomal storage disordersFrom1 Jan 2023 → TodayFunding: FWO research project (including WEAVE projects)
- SRP-Groeifinanciering: “RESTORE”: DEVELOPMENT OF INNOVATIVE GENE THERAPIES FOR GENETIC MUSCLE DISORDERSFrom1 Oct 2022 → TodayFunding: BOF - projects
- TREAT-SARCO: Development of a novel gene therapy strategy for sarcoglycan deficiencyFrom1 Jan 2020 → 31 Dec 2023Funding: FWO research project (including WEAVE projects)
- UPGRADE: Unlocking Precision Gene TherapyFrom1 Jan 2019 → TodayFunding: H2020-EU.3.1. - SOCIETAL CHALLENGES - Health, demographic change and wellbeing
- UPGRADE: Unlocking Precision Gene Therapy (OZR EU Bonus)From1 Jan 2019 → 31 Dec 2023Funding: BOF - Other initiatives
- GENEFIX: Development of muscle-targeted gene therapy for hemophilia B using longer-acting clotting factor IXFrom1 Jan 2016 → 31 Dec 2019Funding: FWO research project (including WEAVE projects)
- Advanced T-cell Therapy for Augmented Cancer Killing ("ATTACK"): next-generation T-cell immunotherapy directed against lymphoid malignanciesFrom1 Jan 2016 → 31 Dec 2019Funding: FWO research project (including WEAVE projects)
- Financing IOF-program GEAR: Hyperactieve Expressie-modulesFrom1 Apr 2014 → 31 Mar 2020Funding: IOF - Industrial Research Fund
- SRP (Groeiers): Next-generation gene therapy by computational vector design and immune stealth nanotechnologyFrom1 Mar 2014 → 28 Feb 2019Funding: BOF - Concerted Research Project from 1994
Publications
41 - 50 of 70
- Chromosomal context and epigenetic mechanisms control the efficacy of genome editing by rare-cutting designer endonucleases.(2012)
Authors: Fayza Daboussi, Mikhail Zaslavskiy, Laurent Poirot, Mariana Loperfido, Agnes Gouble, Valerie Guyot, Sophie Leduc, Roman Galetto, Sylvestre Grizot, Danusia Oficjalska, et al.
Pages: 6367-6379 - Repression of Cardiac Hypertrophy by KLF15: Underlying Mechanisms and Therapeutic Implications.(2012)
Authors: Joost Leenders, Wino Wijnen, Ingeborg Van Der Made, Monika Hiller, M. Swinnen, Thierry VandenDriessche, Marinee K Chuah, Y. Pinto, E. Creemers
Pages: 36754-36754 - Alteration of cardiac progenitor cell potency in GRMD dogs.(2012)
Authors: M. Cassano, E. Berardi, S. Crippa, J. Toelen, I. Barthelemy, R. Micheletti, Marinee K Chuah, Thierry VandenDriessche, Z. Debyser, S. Blot, et al.
Pages: 1945-1967 - Clinical progress in gene therapy: sustained partial correction of the bleeding disorder in patients suffering from severe hemophilia B.(2012)
Authors: Marinee K Chuah, Thierry VandenDriessche
Pages: 4-8 - Gene therapy for von Willebrand’s disease.(2011)Series: von Willebrand’s Disease: Basic and Clinical Aspects
Authors: Marinee K Chuah, I. Petrus, Thierry VandenDriessche, Augusto Federici, Christine Lee, Erik Berntorp, D. Lillicrap, B. Montgomery
Pages: 231-244Number of pages: 14 - Intrinsic cell memory reinforces myogenic commitment of pericyte-derived iPSCs.(2011)
Authors: M. Quattrocelli, G. Palazzolo, G. Floris, P. Schöffski, L. Anastasia, A. Orlacchio, Thierry VandenDriessche, Marinee K Chuah, G. Cossu, C. Verfaillie, et al.
Pages: 593-603 - Codon optimisation of human factor VIII cDNAs leads to high level expression.(2011)
Authors: N. Ward, S. Buckley, S. Waddington, Thierry VandenDriessche, A. Nathwani, J. Mcintosch, E. Tuddenham, C. Kinnon, A. Thrasher, J. Mcvey, et al.
Pages: 798-807 - Retroviral Vectors Induce Epigenetic Chromatin Modifications and IL-10 Production in Transduced B Cells via Activation of Toll-like Receptor 2.(2011)
Authors: R; Ahangarani, W. Janssens, V. Carlier, L. Vander Elst, Marinee K Chuah, M. Jacquemin, J.m. Saint-Remy, Thierry VandenDriessche
Pages: 711-722 - Use of unregulated stem-cell based medicinal products(2010)
Authors: C.a.t. Committee For Advanced Therapies (cat), C.a.t. Cat Scientific Secretariat, Thierry VandenDriessche
Pages: 514-514 - Comparative analysis of transposable element vector systems in human cells.(2010)
Authors: I. Grabundzija, M. Irgang, L. Mátés, E. Belay, J. Matrai, A. Gogol-Döring, K. Kawakami, W. Chen, P. Ruiz, Marinee K Chuah, et al.
Pages: 1200-1209
Patents
1 - 10 of 10
- Vectors for liver-directed gene therapy of hemophilia and methods and use thereof (Inventor)
- Muscle-specific nucleic acid regulatory elements and methods and use thereof (Inventor)
- Optimized liver-specific expression systems for fviii and fix (Inventor)
- Novel combination of nucleic acid regulatory elements and methods and uses thereof (Inventor)
- Novel combination of nucleic acid regulatory elements and methods and uses thereof (Inventor)
- Muscle-specific nucleic acid regulatory elements and methods and use thereof (Inventor)
- Vector for liver-directed gene therapy of hemophilia and methods and use thereof (Inventor)
- Vectors for liver-directed gene therapy of hemophilia and methods and use thereof (Inventor)
- Endothelium-specific nucleic acid regulatory elements and methods and use thereof (Inventor)
- Cardiomyocyte-derived nucleic acid regulatory elements and methods and use thereof (Inventor)