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Researcher
Steven Verhelst
- Disciplines:Organic chemistry, Biochemistry and metabolism, Systems biology, Medical biochemistry and metabolism
Affiliations
- Laboratory of Chemical Biology (Division)
Responsible
From1 Jan 2015 → Today - Laboratory of Chemical Biology (Division)
Member
From1 Jan 2015 → Today
Projects
1 - 10 of 26
- Multi-modal chemical probes as diagnostic toolsFrom1 Oct 2023 → TodayFunding: HORIZON.1.2 - Marie Skłodowska-Curie-actions (MSCA)
- Targeting ATP13A3 for neuroblastoma therapyFrom1 Mar 2023 → TodayFunding: IOF - technology validation in lab
- Profiling of protein depalmitoylation during adipogenesis using activity-based probesFrom1 Nov 2022 → TodayFunding: FWO junior postdoctoral fellowship
- Synthesis and application of novel photoactivable protease probesFrom6 Oct 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- HFSP-grant 2022From1 Oct 2022 → TodayFunding: Foreign private sponsor - undefined
- Synthesis and application of novel photoactivable protease probesFrom12 Sep 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- The development of a novel intracellular Ca2+-buffering agent and its impact on cell functionFrom2 Sep 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Next-generation, multi-technology immune-monitoring and easy-access spectral flow cytometryFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Profiling of protein depalmitoylation during adipogenesis using activity-based probesFrom1 Jan 2022 → 31 Oct 2022Funding: BOF - postdoctoral mandates
- Spatiotemporal control of protease activity by photoactivatable inhibitorsFrom1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
Publications
51 - 60 of 77
- Chemical Probes Targeting Proteases for Imaging and Diagnostics in Cancer(2018)
Authors: Steven Verhelst
Pages: 351 - 376Number of pages: 26 - Protease Specificity Profiling in a Pipet Tip Using "Charge-Synchronized" Proteome-Derived Peptide Libraries(2018)
Authors: Steven Verhelst
Pages: 1923 - 1933 - Benzoxazin-4-ones as novel, easily accessible inhibitors for rhomboid proteases(2018)
Authors: Jian Yang, Marta Barniol-Xicota, Steven Verhelst
Pages: 1423 - 1427 - Simple, scalable and ultra-sensitive tip-based identification of protease substrates(2018)
Authors: Steven Verhelst
Pages: 826 - 834 - Clickable polyamine derivatives as chemical probes for the polyamine transport system(2018)
Authors: Roeland Vanhoutte, Jan Pascal Kahler, Shaun Martin, Sarah van Veen, Steven Verhelst
Pages: 907 - 911 - A modular and generalizable route to potent, selective and pharmacologically compliant inhibitors of rhomboid proteases(2017)
Authors: Steven Verhelst
Pages: 335 - 335 - Activity-based protein profiling(2017)
Authors: Steven Verhelst, Eliane Wolf
Pages: 305 - 333 - Intramembrane proteases as drug targets(2017)
Authors: Steven Verhelst
Pages: 1489 - 1502 - Synthesis and application of activity-based probes for proteases(2017)
Authors: Steven Verhelst
Pages: 255 - 266 - Cleavable Linkers in Chemical Proteomics Applications(2017)
Authors: Steven Verhelst
Pages: 185 - 203
Patents
1 - 1 of 1