Researcher
Steven Verhelst
- Disciplines:Organic chemistry, Biochemistry and metabolism, Systems biology, Medical biochemistry and metabolism
Affiliations
- Laboratory of Chemical Biology (Division)
Responsible
From1 Jan 2015 → Today - Laboratory of Chemical Biology (Division)
Member
From1 Jan 2015 → Today
Projects
1 - 10 of 26
- Multi-modal chemical probes as diagnostic toolsFrom1 Oct 2023 → TodayFunding: HORIZON.1.2 - Marie Skłodowska-Curie-actions (MSCA)
- Targeting ATP13A3 for neuroblastoma therapyFrom1 Mar 2023 → TodayFunding: IOF - technology validation in lab
- Profiling of protein depalmitoylation during adipogenesis using activity-based probesFrom1 Nov 2022 → TodayFunding: FWO junior postdoctoral fellowship
- Synthesis and application of novel photoactivable protease probesFrom6 Oct 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- HFSP-grant 2022From1 Oct 2022 → TodayFunding: Foreign private sponsor - undefined
- Synthesis and application of novel photoactivable protease probesFrom12 Sep 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- The development of a novel intracellular Ca2+-buffering agent and its impact on cell functionFrom2 Sep 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Next-generation, multi-technology immune-monitoring and easy-access spectral flow cytometryFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Profiling of protein depalmitoylation during adipogenesis using activity-based probesFrom1 Jan 2022 → 31 Oct 2022Funding: BOF - postdoctoral mandates
- Spatiotemporal control of protease activity by photoactivatable inhibitorsFrom1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
Publications
31 - 40 of 77
- ATP13A3 is a major component of the enigmatic mammalian polyamine transport system(2021)
Authors: Norin Hamouda, Chris Van den Haute, Roeland Vanhoutte, Johan Swinnen, Patrizia Agostinis, Veerle Baekelandt, Wim Annaert, Steven Verhelst, Jan Eggermont, Peter Vangheluwe
- Kinase Photoaffinity Labeling Reveals Low Selectivity Profile of the IRE1 Targeting Imidazopyrazine-Based KIRA6 Inhibitor(2020)
Authors: Dimitrios Korovesis, Nicole Rufo, Rita Derua, Patrizia Agostinis, Steven Verhelst
Pages: 3106 - 3111 - The synthesis and application of novel activity-based probes for the visualization of cysteine proteases.(2020)
Authors: Merel van de Plassche, Steven Verhelst
- Bioorthogonal Reactions in Activity-Based Protein Profiling(2020)
Authors: Steven Verhelst
- Peptidyl Acyloxymethyl Ketones as Activity-Based Probes for the Main Protease of SARS-CoV-2(2020)
Authors: Merel van de Plassche, Marta Barniol-Xicota, Steven Verhelst
Pages: 3383 - 3388 - Development of photo-activatable protease inhibitors and activity-based probes and their application in the study of dynamic proteolytic processes(2020)
Authors: Suravi Chakrabarty, Steven Verhelst, Lendert Gelens
- Controlled Inhibition of Apoptosis by Photoactivatable Caspase Inhibitors(2020)
Authors: Suravi Chakrabarty, Steven Verhelst
Pages: 1434 - + - Rapid Solid-Phase Construction of Serine Hydrolase Probes Results in Selective Activity-Based Probes for Acyl Protein Thioesterases-1/2(2020)
Authors: Roeland Vanhoutte, Merel van de Plassche, Steven Verhelst
Pages: 11845 - 11853 - Facile Synthesis of Aminomethyl Phosphinate Esters as Serine Protease Inhibitors with Primed Site Interaction(2020)
Authors: Jan Pascal Kahler, Stijn Lenders, Merel van de Plassche, Steven Verhelst
Pages: 1739 - 1744 - Activity-Based Protein Profiling of Serine Proteases in Immune Cells(2020)
Authors: Jan Pascal Kahler, Roeland Vanhoutte, Steven Verhelst
Patents
1 - 1 of 1