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Researcher
Steven Verhelst
- Disciplines:Organic chemistry, Biochemistry and metabolism, Systems biology, Medical biochemistry and metabolism
Affiliations
- Laboratory of Chemical Biology (Division)
Responsible
From1 Jan 2015 → Today - Laboratory of Chemical Biology (Division)
Member
From1 Jan 2015 → Today
Projects
1 - 10 of 26
- Multi-modal chemical probes as diagnostic toolsFrom1 Oct 2023 → TodayFunding: Horizon Europe - Marie Sklodowska-Curie-actions
- Targeting ATP13A3 for neuroblastoma therapyFrom1 Mar 2023 → TodayFunding: IOF - technology validation in lab
- Profiling of protein depalmitoylation during adipogenesis using activity-based probesFrom1 Nov 2022 → TodayFunding: FWO junior postdoctoral fellowship
- Synthesis and application of novel photoactivable protease probesFrom6 Oct 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- HFSP-grant 2022From1 Oct 2022 → TodayFunding: Foreign private sponsor - undefined
- Synthesis and application of novel photoactivable protease probesFrom12 Sep 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- The development of a novel intracellular Ca2+-buffering agent and its impact on cell functionFrom2 Sep 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Next-generation, multi-technology immune-monitoring and easy-access spectral flow cytometryFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Spatiotemporal control of protease activity by photoactivatable inhibitorsFrom1 Jan 2022 → TodayFunding: FWO research project
- Profiling of protein depalmitoylation during adipogenesis using activity-based probesFrom1 Jan 2022 → 31 Oct 2022Funding: BOF - postdoctoral mandates
Publications
1 - 10 of 69
- Furin-targeting activity-based probes with phosphonate and phosphinate esters as warheads(2023)
Authors: Steven Verhelst
Pages: 6498 - 6502 - Ex situ Generation of Thiazyl Trifluoride (NSF₃) as a Gaseous SuFEx Hub(2023)
Authors: Luc Van Meervelt, Steven Verhelst, Ermal Ismalaj, Wim De Borggraeve, Joachim Demaerel
- Mapping Peptide-Protein Interactions by Amine-Reactive Cleavable Photoaffinity Reagents(2023)
Authors: Steven Verhelst
Pages: 25487 - 25495 - Duodenal macrophages control dietary iron absorption via local degradation of transferrin(2023)
Authors: Steven Verhelst
Pages: 2878 - 2890 - Pepstatin-Based Probes for Photoaffinity Labeling of Aspartic Proteases and Application to Target Identification(2023)
Authors: Marc Fransen, Steven Verhelst
Pages: 686 - 692 - Multi-omics approaches to study platelet mechanisms(2023)
Authors: Steven Verhelst
- Clotrimazole-Based Modulators of the TRPM3 Ion Channel Reveal Narrow Structure-Activity Relationship(2023)
Authors: Thomas Voets, Joris Vriens, Steven Verhelst
Pages: 456 - 464 - Efficient Synthesis of an Alkyne Fluorophosphonate Activity‐Based Probe and Applications in Dual Colour Serine Hydrolase Labelling(2023)
Authors: Shanping Ji, Roeland Vanhoutte, Steven Verhelst
- Azapeptide activity-based probes for the SARS-CoV-2 main protease enable visualization of inhibition in infected cells(2023)
Authors: Roeland Vanhoutte, Dirk Jochmans, Steven De Jonghe, Johan Neyts, Steven Verhelst
Pages: 1666 - 1672 - Novel Green Fluorescent Polyamines to Analyze ATP13A2 and ATP13A3 Activity in the Mammalian Polyamine Transport System(2023)
Authors: Roeland Vanhoutte, Chris Van den Haute, Jan Eggermont, Steven Verhelst, Peter Vangheluwe
Patents
1 - 1 of 1