Researcher
Sofie Celen
- Disciplines:Medical imaging and therapy, Medicinal products
Affiliations
- Nuclear Medicine & Molecular Imaging (Division)
Member
From1 Nov 2023 → Today - Radiopharmaceutical Research (Division)
Member
From1 Feb 2004 → Today
Publications
11 - 20 of 49
- F-18-JNJ-64413739, a Novel PET Ligand for the P2X7 Ion Channel: Radiation Dosimetry, Kinetic Modeling, Test-Retest Variability, and Occupancy of the P2X7 Antagonist JNJ-54175446(2019)
Authors: Michel Koole, Corinne Vandermeulen, Donatienne Van Weehaeghe, Sofie Celen, Guy Bormans, Koen Van Laere
Pages: 683 - 690 - Preclinical evaluation of [18F]MA3: a CB2 receptor agonist radiotracer for PET(2019)
Authors: Sofie Celen, Michel Koole, Chris Van den Haute, Wim Vanduffel, Guy Bormans
Pages: 1481 - 1491 - Evaluation of [11C]NMS-E973 as a PET tracer for in vivo visualisation of HSP90(2019)
Authors: Koen Vermeulen, Evelyne Naus, Kaat Luyten, Sofie Celen, Joost Schymkowitz, Frederic Rousseau, Guy Bormans
Pages: 554 - 572 - Fatty Acid Amide Hydrolase Inhibition by JNJ-42165279: A Multiple-Ascending Dose and a Positron Emission Tomography Study in Healthy Volunteers(2018)
Authors: Jan de Hoon, Anne Van Hecken, Sofie Celen, Guy Bormans, Koen Van Laere
Pages: 397 - 404 - First-in-human brain imaging of Alzheimer dementia patients and elderly controls with 18F-MK-6240, a PET tracer targeting neurofibrillary tangle pathology.(2018)
Authors: Rik Vandenberghe, Mathieu Vandenbulcke, Sofie Celen, Guy Bormans, Koen Van Laere
Pages: 107 - 114 - What we observe in vivo is not always what we see in vitro: Development and Validation of C-JNJ-42491293, A novel radioligand for mGluR2(2017)
Authors: Gil Leurquin-Sterk, Sofie Celen, Koen Van Laere, Michel Koole, Guy Bormans, Anne Van Hecken, Alfons Verbruggen, Jan de Hoon
Pages: 110 - 116 - Synthesis and preclinical evaluation of [C-11]MA-PB-1 for in vivo imaging of brain monoacylglycerol lipase (MAGL)(2017)
Authors: Bala Attili, Philippe Berben, Sofie Celen, Michel Koole, Lieven Declercq, Alfons Verbruggen, Guy Bormans
Pages: 104 - 113 - cGMP production of the radiopharmaceutical [F-18]MK-6240 for PET imaging of human neurofibrillary tangles(2017)
Authors: Sofie Celen, Guy Bormans
Pages: 263 - 269 - [18F]JNJ42259152 binding to phosphodiesterase 10A, a key regulator of medium spiny neuron excitability, is altered in the presence of cyclic AMP(2016)
Authors: Bala Attili, Sofie Celen, Michel Koole, Alfons Verbruggen, Koen Van Laere, Guy Bormans
Pages: 897 - 906 - Preclinical evaluation of a P2X7 receptor selective radiotracer: PET studies in a rat model with local overexpression of the human P2X7 receptor and in non-human primates(2016)
Authors: Sofie Celen, Rik Gijsbers, Chris Van den Haute, Michel Koole, Wim Vanduffel, Koen Van Laere, Alfons Verbruggen, Zeger Debyser, Guy Bormans
Pages: 1436 - 1441