< Back to previous page
Researcher
Siska Van Belle
- Disciplines:Microbiology, Systems biology, Biomaterials engineering, Biological system engineering, Biomechanical engineering, Other (bio)medical engineering, Environmental engineering and biotechnology, Industrial biotechnology, Other biotechnology, bio-engineering and biosystem engineering, Laboratory medicine
Affiliations
- Molecular Virology and Gene Therapy (Division)
Member
From16 Aug 2016 → Today
Projects
1 - 1 of 1
- Development of a new therapeutic strategy for the treatment of MLL-rearranged acute leukemiaFrom1 Jan 2017 → 16 Nov 2022Funding: FWO Strategic Basic Research Grant
Publications
1 - 10 of 10
- The Impact of Lens Epithelium-Derived Growth Factor p75 Dimerization on Its Tethering Function(2024)
Authors: Siska Van Belle, Zeger Debyser
- Development of a new therapeutic strategy for the treatment of MLL-rearranged acute leukemia(2022)
Authors: Siska Van Belle, Zeger Debyser, Frauke Christ
- Design, synthesis, in silico studies, and antiproliferative evaluations of novel indolin-2-one derivatives containing 3-hydroxy-4-pyridinone fragment(2022)
Authors: Siska Van Belle, Zeger Debyser, Frauke Christ
- LEDGF/p75-mediated chemoresistance of mixed-lineage leukemia involves cell survival pathways and super enhancer activators(2022)
Authors: Siska Van Belle, Tine Brouns, Marianne Carlon, Frauke Christ, Zeger Debyser
Pages: 133 - 140 - Unlike its Paralog LEDGF/p75, HRP-2 Is Dispensable for MLL-R Leukemogenesis but Important for Leukemic Cell Survival(2021)
Authors: Siska Van Belle, Frauke Christ, Zeger Debyser
- LEDGINs, Inhibitors of the Interaction Between HIV-1 Integrase and LEDGF/p75, Are Potent Antivirals with a Potential to Cure HIV Infection(2021)
Authors: Zeger Debyser, Anne Bruggemans, Siska Van Belle, Julie Janssens, Frauke Christ
Pages: 97 - 114 - Synthesis, anti-HIV-1 and antiproliferative evaluation of novel 4-nitroimidazole derivatives combined with 5-hydroxy-4-pyridinone moiety(2020)
Authors: Siska Van Belle, Zeger Debyser, Frauke Christ
- De Novo Mutations Affecting the Catalytic Cα Subunit of PP2A (PPP2CA) Cause Syndromic Intellectual Disability Resembling Other PP2A-Related Neurodevelopmental Disorders.(2019)
Authors: Saar Reynhout, Siska Van Belle, Veerle Janssens
Pages: 139 - 156 - Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation(2018)
Authors: Jan De Rijck, Jonas Demeulemeester, Siska Van Belle, Frauke Christ, Zeger Debyser
Pages: E7053 - E7062 - LEDGF/p75 is dispensable for hematopoiesis but essential for MLL-rearranged leukemogenesis(2017)
Authors: Sara Elashkar, Jonas Demeulemeester, Frauke Christ, Siska Van Belle, Nancy Boeckx, Zeger Debyser, Jan De Rijck
Pages: 95 - 107