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Researcher
Sergei Strelkov
- Disciplines:Analytical chemistry, Medicinal and biomolecular chemistry, Biochemistry and metabolism, Molecular and cell biology, Plant biology, Systems biology, Biophysics, Medical biochemistry and metabolism, Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences
Affiliations
- Biocrystallography (Division)
Responsible
From1 Jan 2012 → Today - Biocrystallography (Division)
Member
From1 Dec 2005 → Today
Projects
31 - 38 of 38
- Exploiting the BH4 domain of Bcl-2 as a novel target for the development of peptidomimetics that promote pro-apoptotic Ca2+ signaling.From1 Jan 2011 → 31 Dec 2014Funding: FWO research project (including WEAVE projects)
- Unravelling the regulatory roles of defective invertases in plantsFrom1 Oct 2010 → 1 Oct 2014Funding: BOF - Doctoral projects
- Structural studies of human small heat shock proteins and their complexes (SHSPCOMPLEX).From1 Sep 2010 → 31 Aug 2014Funding: Marie Curie - People
- Crystallographic Studies of Vimentin and Lamin AFrom1 Nov 2009 → 5 Dec 2013Funding: Own budget, for example: patrimony, inscription fees, gifts
- Structure determination of prokaryote ion channels.From1 Jan 2009 → 31 Dec 2012Funding: FWO research project (including WEAVE projects)
- Structural and functional study of the central GTPase/kinase catalytic core of LRRK2, a Parkinson's disease-linked protein.From1 Jan 2009 → 31 Dec 2014Funding: FWO research project (including WEAVE projects)
- Intergrated macromolecular christallography core-facility.From20 Oct 2008 → 19 Apr 2015Funding: Hercules - Small and Medium size research infrastructure
- Structure determination of prokaryotic and eukaryotic ion channels.From1 Oct 2008 → 30 Sep 2013Funding: BOF - Concerted Research Project from 1994
Publications
1 - 10 of 103
- Development of new antimicrobials: Rational design of polyomavirus and mycobacterial inhibitors(2023)
Authors: Stijn Lenders, Peter Verwilst, Sergei Strelkov, Arthur Van Aerschot
- Molecular structure of soluble vimentin tetramers(2023)
Authors: Pieter-Jan Vermeire, Jeremy Harvey, Sergei Strelkov
- Novel Insights Into Intermediate Filament Assembly Through Chemical Cross-Linking(2023)
Authors: Pieter-Jan Vermeire, Sergei Strelkov
- 5-(Perylen-3-ylethynyl)uracil as an antiviral scaffold: Potent suppression of enveloped virus reproduction by 3-methyl derivatives in vitro(2023)
Authors: Sergei Strelkov
- Stability profile of vimentin rod domain(2022)
Authors: Simon Leekens, Pieter-Jan Vermeire, Jeremy Harvey, Sergei Strelkov
- Structural Basis of Cysteine Ligase MshC Inhibition by Cysteinyl-Sulfonamides(2022)
Authors: Stijn Lenders, Evgenii Osipov, Jef Rozenski, Sergei Strelkov, Arthur Van Aerschot
- Partitioning of the initial catalytic steps of leucyl-tRNA synthetase is driven by an active site peptide-plane flip(2022)
Authors: Sergei Strelkov, Arthur Van Aerschot
- Discovery of novel druggable pockets on polyomavirus VP1 through crystallographic fragment-based screening to develop capsid assembly inhibitors(2022)
Authors: Evgenii Osipov, Arthur Van Aerschot, Sergei Strelkov
- Integrative Structural Biology Approach to Intermediate Filaments(2022)
Authors: Anastasia Lilina, Sergei Strelkov
- Molecular Interactions Driving Intermediate Filament Assembly(2021)
Authors: Pieter-Jan Vermeire, Giel Stalmans, Anastasia Lilina, Sergei Strelkov