Researcher
Serge Van Calenbergh
- Keywords:medicinal chemistry, nucleoside analogues, drug discovery, infectious diseases, glycosphingolipids
- Disciplines:Organic chemical synthesis, Bio-organic chemistry, Characterisation of biologically active (macro)molecules, Medicinal and biomolecular chemistry not elsewhere classified, Biomolecular modelling and design, Medicinal chemistry, Drug discovery and development not elsewhere classified
Affiliations
- Faculty Education Services Pharmaceutical Sciences (Administrative office)
Responsible
From1 Oct 2014 → 30 Sep 2022 - Faculty Education Services Pharmaceutical Sciences (Administrative office)
Member
From1 Oct 2014 → 30 Sep 2022 - Dean's Office of the Faculty of Pharmaceutical Sciences (Administrative office)
Member
From1 Sep 1997 → 31 Dec 1997 - Department of Pharmaceutics (Department)
Member
From1 Jan 1993 → Today
Projects
1 - 10 of 15
- Design and synthesis of inhibitors of the MEP pathwayFrom1 Jan 2024 → TodayFunding: BOF - doctoral mandates
- Uncaging the potential of photopharmacology for the treatment of epilepsyFrom1 Jan 2024 → TodayFunding: FWO research project (including WEAVE projects)
- Evaluation of a new treatment against "blackhead" disease in turkeys (POULTRY 2)From16 Oct 2023 → TodayFunding: IOF - technology validation in lab
- Cofunding core facility - NMR Expertise CentreFrom1 Oct 2023 → TodayFunding: BOF - research organisations
- Identification of optimized Aurora Kinase A PROTACs with suitable PK properties for in vivo proof-of-concept studies (OPTIMAPK).From15 Jul 2023 → TodayFunding: IOF - technology concept exploration
- Targeting transcription factor addiction in acute leukemia (TaTFAL)From1 Oct 2021 → TodayFunding: FWO Strategic Basic Research (SBO)
- Targeting the degradation of proteins involved in neuroblastoma with bivalent ligands.From1 Nov 2020 → TodayFunding: FWO Strategic Basic Research Grant
- Novel treatment for blackhead disease in turkeysFrom3 Aug 2020 → 30 Jun 2022Funding: IOF - technology concept exploration
- Exploiting the methylerythritol phosphate pathway as a source of drug targets for novel anti-infectivesFrom1 Apr 2020 → TodayFunding: H2020-EU.1.3.- EXCELLEN SCIENCE - Marie Skłodowska-Curie actions
- Identification of adaptive mechanisms leading to reduced antibiotic susceptibility in bacterial biofilms using experimental evolution and machine learning approachesFrom1 Jan 2020 → TodayFunding: BOF - projects
Publications
31 - 38 of 38
- Unbreakable codes in electrospun fibers to stop medicine counterfeiting(2010)Volume: 148
Authors: Chaobo Huang, Bart Lucas, Chris Vervaet, Kevin Braeckmans, Serge Van Calenbergh, Izet Karalic, Mado Vandewoestyne, Dieter Deforce, Jo Demeester, Stefaan De Smedt
Pages: e13 - e15 - Receptor-mediated targeting of cathepsins in professional antigen presenting cells(2009)
Authors: Wrik Hillaert, Martijn Verdoes, Bogdan I Florea, Athanasios Saragliadis, Kim LL Habets, Johan Kuiper, Serge Van Calenbergh, Ferry Ossendorp, Gijsbrecht A van der Marel, Christoph Driessen, et al.
Pages: 1629 - 1632 - Human mitochondrial thymidine kinase is selectively inhibited by 3'-thiourea derivatives of beta-thymidine: identification of residues crucial for both inhibition and catalytic activity(2009)
Authors: Jan Balzarini, Ineke Van Daele, Ana Negri, Nicola Solaroli, Anna Karlsson, Sandra Liekens, Frederico Gago, Serge Van Calenbergh
Pages: 1127 - 1136 - Triplex formation by pyrene-labelled probes for nucleic acid detection in fluorescence assays(2008)
Authors: Ineke Van Daele, N Bomholt, VV Filichev, Serge Van Calenbergh, E Pedersen
Pages: 791 - 801 - Synthesis of analogues of (E)-1-hydroxy-2-methylbut-2-enyl 4-diphosphate, an isoprenoid precursor and human γδ T cell activator(2008)
Authors: Steven Van Hoof, Carl Jeffrey Lacey, Rene C Röhrich, Jochen Wiesner, Hassan Jomaa, Serge Van Calenbergh
Pages: 1365 - 1370 - From M-tuberculosis thymidine monophosphate kinase (TMPKmt) inhibitors towards mitochondrial thymidine kinase (TK-2) inhibitors(2008)Volume: 10
Authors: Serge Van Calenbergh, I Van Daele, Sara Van Poecke, M Froeyen, H Munier Lehmann, J Balzarini
Pages: 87 - 93 - Towards new antimalarial drugs: Synthesis of non-hydrolyzable phosphate mimics as feed for a predictive QSAR study on 1-deoxy-D-xylulose-5-phosphate reductoisomerase inhibitors(2008)
Authors: D Giessmann, P Heidler, Timothy Haemers, Serge Van Calenbergh, A Reichenberg, H Jomaa, C Weidemeyer, S Sanderbrand, J Wiesner, A Link
Pages: 653 - 656 - Synthesis and potency of novel uracil nucleotides and derivatives as P2Y(2) and P2Y(6) receptor agonists(2008)
Authors: HJ Ko, RL Carter, Liesbet Cosyn, R Petrelli, S de Castro, P Besada, YX Zhou, L Cappellacci, P Franchetti, M Grifantini, et al.
Pages: 6319 - 6332
Patents
1 - 10 of 10
- Nucleoside analogues for the treatment of parasitic infections (Inventor)
- Sphingamide Compounds and Methods for Binding iNKT Cells (Inventor)
- Nucleoside analogues for the treatment of parasitic infections (Inventor)
- Sphingamide Compounds and Methods for Binding iNKT Cells (Inventor)
- GALACTOPYRANOSYL DERIVATIVES USEFUL AS MEDICAMENTS (Inventor)
- Nucleoside analogues for the treatment of parasitic infections (Inventor)
- HAMAMELITANNIN ANALOGUES AND USES THEREOF (Inventor)
- HAMAMELITANNIN ANALOGUES AND USES THEREOF (Inventor)
- NOVEL HAMAMELITANNIN ANALOGUES AND USES THEREOF (Inventor)
- GALACTOPYRANOSYL DERIVATIVES USEFUL AS MEDICAMENTS (Inventor)