Researcher
Sarah-Maria Fendt
- Disciplines (Flanders Institute for Biotechnology):Analysis of next-generation sequence data, Cell death, Cancer biology
- Disciplines (KU Leuven):Biochemistry and metabolism, Medical systems biology, Molecular and cell biology, Oncology
- See also: Fendt SM (Flanders Institute for Biotechnology)
Affiliations
- Laboratory of Cellular Metabolism and Metabolic Regulation (VIB-KU Leuven) (Division)
Responsible
From1 Oct 2013 → Today - Fendt Lab (Research group)
Responsible
From1 Jan 2017 → Today - Laboratory of Cellular Metabolism and Metabolic Regulation (VIB-KU Leuven) (Division)
Member
From1 Jan 2013 → Today
Projects
1 - 10 of 40
- The Role of Metabolism in Metastasis FormationFrom27 Feb 2024 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Targeting cell surface receptors to inhibit metastatic growthFrom1 Jan 2024 → TodayFunding: FWO research project (including WEAVE projects)
- Targeting Mfrn2 to inhibit breast cancer-derived metastasis formation in lung and liver.From1 Oct 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Dissecting the dependence of liver metastases on the hypoxia-induced expression of nutrient transporters.From1 Oct 2023 → 2 Oct 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Development of Spatial metabolomics methods by DESI and MALDI for cancer researchFrom25 Aug 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Lipid metabolism in obesity and aging-induced cancer metastasisFrom1 Jan 2023 → TodayFunding: Foundations, funds and other with scientific goal
- Dissecting the heterotypic cell communication networks at the perivascular niche to detect andintercept the early metastatic processFrom1 Jan 2023 → TodayFunding: BOF - iBOF
- Inhibiting iron metabolism to target metastasesFrom1 Oct 2022 → TodayFunding: BOF - projects
- Predicting metastasis formation based on cancer cells with a distinct energy metabolismFrom1 Oct 2022 → TodayFunding: BOF - projects
- Desorption electrospray ionization multi reflecting TOF: DESI XS SELECT SERIES MRTFrom2 Aug 2022 → TodayFunding: Other federal scientific institutions
Publications
21 - 30 of 127
- Reversal of mitochondrial malate dehydrogenase 2 enables anaplerosis via redox rescue in respiration-deficient cells(2022)
Authors: Anke Vandekeere, Sarah-Maria Fendt
Pages: 4537 - + - CD8+ T cell metabolic rewiring defined by scRNA-seq identifies a critical role of ASNS expression dynamics in T cell differentiation(2022)
Authors: dorien Broekaert, Elodie Modave, Peter Carmeliet, Diether Lambrechts, Sarah-Maria Fendt
- Serum methylmalonic acid concentrations at breast cancer diagnosis are not associated with distant metastases(2022)
Authors: Sigrid Hatse, Anke Vandekeere, Yentl Lambrechts, François Richard, Sarah-Maria Fendt, Hans Wildiers
Pages: S76 - S77 - GBM tumors are heterogeneous in their fatty acid metabolism and modulating fatty acid metabolism sensitizes cancer cells derived from recurring GBM tumors to temozolomide(2022)
Authors: Steven De Vleeschouwer, Raf Sciot, Jenny Weng, Francesca Bosisio, Gabriele Bergers, Frederik De Smet, Diether Lambrechts, Sarah-Maria Fendt
- Metabolite-derived protein modifications modulating oncogenic signaling(2022)
Authors: Anke Vandekeere, Sarah-Maria Fendt
- PFKFB4 interacts with FBXO28 to promote HIF-1α signaling in glioblastoma(2022)
Authors: Sarah-Maria Fendt
- Editorial overview: The metabolic network(2022)
Authors: Sarah-Maria Fendt
- PHGDH heterogeneity potentiates cancer cell dissemination and metastasis (vol 605. pg 747, 2022)(2022)
Authors: Margherita Demicco, Anke Vandekeere, Juan Fernandez Garcia, Carla Riera Domingo, David Nittner, Francesca Rizzollo, Panagiotis Karras, dorien Broekaert, Sofie Demeyer, Ayse Bassez, et al.
Pages: E8 - E8 - Metastasis(2022)
Authors: Sarah-Maria Fendt
Pages: 787 - 791 - Serine metabolism remodeling after platinum-based chemotherapy identifies vulnerabilities in a subgroup of resistant ovarian cancers(2022)
Authors: Ali Talebi, Wout De Wispelaere, Regina Esi Mensimah Baiden-Amissah, Guy Eelen, Emanuele Berardi, Johan Swinnen, Peter Carmeliet, Diether Lambrechts, Sarah-Maria Fendt, Daniela Annibali, et al.