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Researcher
Sandra Liekens
- Disciplines:Microbiology, Systems biology, Laboratory medicine
Affiliations
- Department of Microbiology, Immunology and Transplantation (Department)
Member
From1 Dec 2019 → Today - Laboratory of Virology and Chemotherapy (Rega Institute) (Division)
Member
From1 Oct 1999 → 31 Dec 2019
Projects
1 - 7 of 7
- Structure-based discovery of positive allosteric modulators of the alpha7 nicotinic acetylcholine receptor as cognition enhancers.From1 Oct 2016 → 30 Sep 2018Funding: IOF - Industrial Research Fund
- Vascular-disrupting agents (VDA): mechanism of action and anti-tumor activityFrom1 Feb 2016 → 6 Jan 2017Funding: Own budget, for example: patrimony, inscription fees, gifts
- An automated platform for multiparameter data collection on live pathogens of higher or unknown biosafety risk.From26 Jun 2014 → 31 Dec 2018Funding: Hercules - Large scale research infrastructure
- Role of receptor tyrosine kinases and associated gangliosides in influenza virus replicationFrom1 Oct 2012 → 21 Dec 2020Funding: BOF - Doctoral projects
- Mechanistic study on virus entry and replication. A fundamental approach to the development of new and specific antiviral chemotherapeutics.From1 Jan 2010 → 31 Dec 2014Funding: BOF - Concerted Research Project from 1994
- Dengue virus infection of endothelial cells: Pathogenesis and antiviral potential of glycosaminoglycan targetingFrom1 Sep 2009 → 29 Sep 2015Funding: Own budget, for example: patrimony, inscription fees, gifts
- The effect of Mycoplasma enzymes on the antiviral and anticancer activity of nucleoside analoguesFrom1 Jun 2008 → 2 Dec 2013Funding: IWT personal funding - strategic basic research grants
Publications
1 - 10 of 113
- Benzothiazole Derivatives as Multifunctional Antioxidant Agents for Skin Damage: Structure-Activity Relationship of a Scaffold Bearing a Five-Membered Ring System(2022)
Authors: Jan Balzarini, Sandra Liekens
- Design, Synthesis, Spectroscopic Characterisation and In Vitro Cytostatic Evaluation of Novel Bis(coumarin-1,2,3-triazolyl)benzenes and Hybrid Coumarin-1,2,3-triazolyl-aryl Derivatives(2022)
Authors: Sandra Liekens
- Transition metal-catalyzed synthesis of new 3-substituted coumarin derivatives as antibacterial and cytostatic agents(2021)
Authors: Sandra Liekens
Pages: 1865 - 1884 - Benzazole Substituted Iminocoumarins as Potential Antioxidants with Antiproliferative Activity(2021)
Authors: Sandra Liekens
Pages: 13 - 20 - N-alpha-Aminoacyl Colchicines as Promising Anticancer Agents(2021)
Authors: Sam Noppen, Sandra Liekens
Pages: 21 - 32 - Skin Damages-Structure Activity Relationship of Benzimidazole Derivatives Bearing a 5-Membered Ring System(2020)
Authors: Jan Balzarini, Sandra Liekens
- Design, synthesis and evaluation of benzothiazole derivatives as multifunctional agents(2020)
Authors: Jan Balzarini, Sandra Liekens
- Synthesis and Biological Evaluation of Analogs of Didehydroepiandrosterone as Potential New Anticancer Agents(2020)
Authors: Sandra Liekens
- Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3′,4′,5′-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold(2020)
Authors: Jan Balzarini, Sandra Liekens
- Gelatinase B/matrix metalloproteinase-9 and other neutrophil proteases switch off interleukin-2 activity(2019)
Authors: Vasily Rybakin, Sam Noppen, Jennifer Vandooren, Sandra Liekens, Paul Proost
Pages: 2191 - 2208
Patents
1 - 2 of 2
- Novel anti-cancer thiophene compounds (Inventor)
- Anti-cancer compounds (Inventor)