Researcher
Sabine Tejpar
- Disciplines:Oncology
Affiliations
- Digestive Oncology (Division)
Responsible
From1 Aug 2022 → Today - Digestive Oncology (Division)
Member
From1 Aug 2022 → Today - Molecular Digestive Oncology (Division)
Member
From1 Jan 2012 → 31 Jul 2022 - Translational Research in GastroIntestinal Disorders (Division)
Member
From1 Oct 2003 → 31 Dec 2011
Projects
31 - 40 of 56
- Single-cell metatranscriptomics in the human gut microbiotaFrom1 Oct 2020 → 30 Sep 2023Funding: FWO senior postdoctoral fellowship
- OrganID: Organ-derived complex 2D/3D cultures in human diseaseFrom1 Oct 2020 → TodayFunding: FWO Strategic Basic Research (SBO)
- Translational research-oriented technology platform for single cell analysisFrom1 May 2020 → TodayFunding: BOF - scientific equipment program
- Characterization of the phenotypic plasticity of IL17-producing T cells during colorectal cancer development and their interactions with the microbiomeFrom1 Jan 2020 → 31 Dec 2023Funding: FWO research project
- Microsatellite Instability in Colorectal Cancer: Foundation of Precision Medicine in Three sub-Saharan African countries.From1 Jan 2020 → 31 Aug 2022Funding: VLIR-UOS South Initiatives
- The pro-tumorigenic crosstalk between enteric glia and macrophages in colorectal cancerFrom1 Apr 2019 → 1 Apr 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Integrated IMMUnoprofiling of large adaptive CANcer patients cohortsFrom1 Mar 2019 → TodayFunding: H2020-EU.3.1. - SOCIETAL CHALLENGES - Health, demographic change and wellbeing, H2020 - European Institute of Innovation and Technology
- Profiling of the colorectal tumor (CRC) immune microenvironment (TME) to identify novel therapeutic opportunities and biomarkersFrom1 Jan 2019 → 31 Dec 2021Funding: Foundations, funds and other with scientific goal
- Exploring the role of microbiome-immune interactions in colorectal cancer development and immune evasionFrom1 Oct 2018 → 30 Sep 2021Funding: FWO fellowships
- Mass cytometry by time-of-flight: next-generation flow cytometry for multiplexed single cell analysisFrom1 May 2018 → 30 Apr 2022Funding: FWO Medium Size Research Infrastructure
Publications
1 - 10 of 250
- Discovery of non-genomic drivers of YAP signaling modulating the cell plasticity in CRC tumor lines.(2024)
Authors: Pavlo Lutsik, Sabine Tejpar
Pages: 109247 - CD4+ T cell activation distinguishes response to anti-PD-L1+anti-CTLA4 therapy from anti-PD-L1 monotherapy.(2024)
Authors: Amelie Franken, Michel Bila, Aurelie Mechels, Jeroen Van Dessel, Bram Boeckx, Sigrid Hatse, Esther Hauben, Vincent Vander Poorten, Katy Vandereyken, Sabine Tejpar, et al.
Pages: 541 - 558.e7 - Cell type signatures in cell-free DNA fragmentation profiles reveal disease biology.(2024)
Authors: Tatjana Jatsenko, Stefania Tuveri, Lore Lannoo, Kristel Van Calsteren, Liesbeth Lenaerts, Sabine Tejpar, Bernard Thienpont, Joris Vermeesch
Pages: 2220 - Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer(2024)
Authors: Sabine Tejpar
- Image-based multiplex immune profiling of cancer tissues: translational implications. A report of the International Immuno-oncology Biomarker Working Group on Breast Cancer(2024)
Authors: Sara Verbandt, An Coosemans, Sabine Tejpar
- Lymph node and tumor-associated PD-L1+macrophages antagonize dendritic cell vaccines by suppressing CD8+T cells(2024)
Authors: Jenny Sprooten, Isaure Vanmeerbeek, Sabine Tejpar, Steven De Vleeschouwer, Abhishek Garg
- Neoantigen identification: Technological advances and challenges.(2024)
Authors: Sabine Tejpar, Sara Verbandt
Pages: 265 - 302 - Trial watch: chemotherapy-induced immunogenic cell death in oncology(2023)
Authors: Jenny Sprooten, Isaure Vanmeerbeek, Stefan Naulaerts, Lisa Kinget, An Coosemans, Steven De Vleeschouwer, Els Wauters, Sabine Tejpar, Benoit Beuselinck, Sigrid Hatse, et al.
- Efficacy of olaparib in advanced cancers with germline or somatic mutations in BRCA1, BRCA2, CHEK2 and ATM, a Belgian Precision tumor-agnostic phase II study(2023)
Authors: Sabine Tejpar
- Single cell dynamics of tumor specificity vs bystander activity in CD8+ T cells define the diverse immune landscapes in colorectal cancer(2023)
Authors: Sara Verbandt, Isaure Vanmeerbeek, Jenny Sprooten, Gert De Hertogh, Xavier Sagaert, Albert Wolthuis, Stefan Naulaerts, Sabine Tejpar, Abhishek Garg
Patents
1 - 1 of 1
- Colon cancer (Inventor)