Researcher
Sabine Tejpar
- Disciplines:Oncology
Affiliations
- Digestive Oncology (Division)
Responsible
From1 Aug 2022 → Today - Digestive Oncology (Division)
Member
From1 Aug 2022 → Today - Molecular Digestive Oncology (Division)
Member
From1 Jan 2012 → 31 Jul 2022 - Translational Research in GastroIntestinal Disorders (Division)
Member
From1 Oct 2003 → 31 Dec 2011
Projects
21 - 30 of 56
- Expression of the metabolite transporter SLC4A4 in pancreatic cancer cells promotes immuneescape and resistance to immunotherapyFrom1 Oct 2021 → TodayFunding: IOF - technology validation in lab
- Understanding and tackling T cell dysfunctions towards improving colorectal cancer therapies.From6 Sep 2021 → TodayFunding: FWO Strategic Basic Research Grant
- The immunosuppressive environment of colorectal cancer, single cell and functional characterizationFrom2 Jul 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Exploring the added value of exosome-mediated dual targeting in the treatment of pancreatic ductal adenocarcinomaFrom15 May 2021 → 14 May 2023Funding: BOF - various
- Revealing novel immunomodulatory myeloid niches for improving colorectal cancer immunotherapyFrom19 Apr 2021 → TodayFunding: FWO Strategic Basic Research Grant
- Establishment of CRC mouse models and interference with CD4/DC /CD8 dysfunction to improve colorectal cancer therapyFrom1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- Unraveling of protective innate and adaptive immune responses to SARS-CoV-2 in the setting of HCoV crossreactivityFrom1 Jan 2021 → 31 Dec 2022Funding: IOF - technology validation in lab
- Spectral flowcytometry (Cytek Aurora)From1 Jan 2021 → 31 Dec 2022Funding: BOF - scientific equipment program
- MIMICRY - Modulating Immunity and the Microbiome for effective CRC ImmunotherapyFrom1 Jan 2021 → TodayFunding: BOF - iBOF
- Coevolution of epithelium and immune response in colorectal cancer: comprehensive longitudinal analysis and manipulation of crosstalk leading to exhausted responses in dedicated mouse models.From1 Jan 2021 → 29 Feb 2024Funding: Foundations, funds and other with scientific goal
Publications
1 - 10 of 250
- Discovery of non-genomic drivers of YAP signaling modulating the cell plasticity in CRC tumor lines.(2024)
Authors: Pavlo Lutsik, Sabine Tejpar
Pages: 109247 - CD4+ T cell activation distinguishes response to anti-PD-L1+anti-CTLA4 therapy from anti-PD-L1 monotherapy.(2024)
Authors: Amelie Franken, Michel Bila, Aurelie Mechels, Jeroen Van Dessel, Bram Boeckx, Sigrid Hatse, Esther Hauben, Vincent Vander Poorten, Katy Vandereyken, Sabine Tejpar, et al.
Pages: 541 - 558.e7 - Cell type signatures in cell-free DNA fragmentation profiles reveal disease biology.(2024)
Authors: Tatjana Jatsenko, Stefania Tuveri, Lore Lannoo, Kristel Van Calsteren, Liesbeth Lenaerts, Sabine Tejpar, Bernard Thienpont, Joris Vermeesch
Pages: 2220 - Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer(2024)
Authors: Sabine Tejpar
- Image-based multiplex immune profiling of cancer tissues: translational implications. A report of the International Immuno-oncology Biomarker Working Group on Breast Cancer(2024)
Authors: Sara Verbandt, An Coosemans, Sabine Tejpar
- Lymph node and tumor-associated PD-L1+macrophages antagonize dendritic cell vaccines by suppressing CD8+T cells(2024)
Authors: Jenny Sprooten, Isaure Vanmeerbeek, Sabine Tejpar, Steven De Vleeschouwer, Abhishek Garg
- Neoantigen identification: Technological advances and challenges.(2024)
Authors: Ting Pu, Sabine Tejpar, Sara Verbandt
Pages: 265 - 302 - Trial watch: chemotherapy-induced immunogenic cell death in oncology(2023)
Authors: Jenny Sprooten, Isaure Vanmeerbeek, Stefan Naulaerts, Lisa Kinget, An Coosemans, Steven De Vleeschouwer, Els Wauters, Sabine Tejpar, Benoit Beuselinck, Sigrid Hatse, et al.
- Efficacy of olaparib in advanced cancers with germline or somatic mutations in BRCA1, BRCA2, CHEK2 and ATM, a Belgian Precision tumor-agnostic phase II study(2023)
Authors: Sabine Tejpar
- Single cell dynamics of tumor specificity vs bystander activity in CD8+ T cells define the diverse immune landscapes in colorectal cancer(2023)
Authors: Sara Verbandt, Isaure Vanmeerbeek, Jenny Sprooten, Gert De Hertogh, Xavier Sagaert, Albert Wolthuis, Stefan Naulaerts, Sabine Tejpar, Abhishek Garg
Patents
1 - 1 of 1
- Colon cancer (Inventor)